Zic2 Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description Zic family member 2|This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7546)
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Genes

67 target genes of the Zic2 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
ADAR adenosine deaminase, RNA-specific
ARL5B ADP-ribosylation factor-like 5B
BCL6 B-cell CLL/lymphoma 6
CFC1B cripto, FRL-1, cryptic family 1B
CHD2 chromodomain helicase DNA binding protein 2
CNTNAP1 contactin associated protein 1
CXXC5 CXXC finger protein 5
DCAF6 DDB1 and CUL4 associated factor 6
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNER delta/notch-like EGF repeat containing
DYNLL1 dynein, light chain, LC8-type 1
EDC4 enhancer of mRNA decapping 4
ERBB3 erb-b2 receptor tyrosine kinase 3
ERF Ets2 repressor factor
ETV6 ets variant 6
EXTL3 exostosin-like glycosyltransferase 3
FANCD2 Fanconi anemia, complementation group D2
FNDC1 fibronectin type III domain containing 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
FUBP3 far upstream element (FUSE) binding protein 3
FUS FUS RNA binding protein
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GHR growth hormone receptor
GMPPB GDP-mannose pyrophosphorylase B
GTF2IRD1 GTF2I repeat domain containing 1
HEXIM2 hexamethylene bis-acetamide inducible 2
IGDCC4 immunoglobulin superfamily, DCC subclass, member 4
IRF2BP2 interferon regulatory factor 2 binding protein 2
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KIAA1467 KIAA1467
LAMC2 laminin, gamma 2
LINC00838 long intergenic non-protein coding RNA 838
LMF1 lipase maturation factor 1
LOC100128176 uncharacterized LOC100128176
LOC100652824
MAP7D1 MAP7 domain containing 1
MEG3 maternally expressed 3 (non-protein coding)
MEI1 meiosis inhibitor 1
NARR nine-amino acid residue-repeats
NR2F1-AS1 NR2F1 antisense RNA 1
NTN3 netrin 3
PATE2 prostate and testis expressed 2
PHACTR2 phosphatase and actin regulator 2
PITX1 paired-like homeodomain 1
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP6R3 protein phosphatase 6, regulatory subunit 3
PRR3 proline rich 3
PTPRF protein tyrosine phosphatase, receptor type, F
RARA retinoic acid receptor, alpha
S100A1 S100 calcium binding protein A1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SOX8 SRY (sex determining region Y)-box 8
STAC3 SH3 and cysteine rich domain 3
SYNPO2 synaptopodin 2
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TENM3 teneurin transmembrane protein 3
THADA thyroid adenoma associated
THSD7B thrombospondin, type I, domain containing 7B
TSNAXIP1 translin-associated factor X interacting protein 1
TYROBP TYRO protein tyrosine kinase binding protein
UBE2I ubiquitin-conjugating enzyme E2I
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
ZDHHC5 zinc finger, DHHC-type containing 5
ZNF462 zinc finger protein 462
ZNRF3 zinc and ring finger 3