Zidovudine Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A pyrimidine 2',3'-dideoxyribonucleoside compound having a 3'-azido substituent and thymine as the nucleobase. (Chemical Entities of Biological Interest Ontology, CHEBI_10110)
External Link http://ctdbase.org/detail.go?type=chem&acc=D015215
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Genes

78 genes/proteins interacting with the chemical Zidovudine from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADA adenosine deaminase
ADIPOQ adiponectin, C1Q and collagen domain containing
ALB albumin
APRT adenine phosphoribosyltransferase
BCL2 B-cell CLL/lymphoma 2
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAT catalase
CCL2 chemokine (C-C motif) ligand 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
COX1
COX2
COX5A cytochrome c oxidase subunit Va
COX5B cytochrome c oxidase subunit Vb
COX6C cytochrome c oxidase subunit VIc
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
COX7B cytochrome c oxidase subunit VIIb
COX7C cytochrome c oxidase subunit VIIc
CS citrate synthase
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
DMD dystrophin
DTYMK deoxythymidylate kinase (thymidylate kinase)
EDN1 endothelin 1
EPO erythropoietin
EPOR erythropoietin receptor
ESR1 estrogen receptor 1
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FASN fatty acid synthase
GATA1 GATA binding protein 1 (globin transcription factor 1)
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
GYPA glycophorin A (MNS blood group)
HRAS Harvey rat sarcoma viral oncogene homolog
IFNA1 interferon, alpha 1
IFNG interferon, gamma
IL10 interleukin 10
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL2RA interleukin 2 receptor, alpha
IL3 interleukin 3
IL6 interleukin 6
IRF4 interferon regulatory factor 4
KRAS Kirsten rat sarcoma viral oncogene homolog
LEP leptin
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MUT methylmalonyl CoA mutase
MYH7 myosin, heavy chain 7, cardiac muscle, beta
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
NFE2 nuclear factor, erythroid 2
NOS3 nitric oxide synthase 3 (endothelial cell)
PPARG peroxisome proliferator-activated receptor gamma
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SOD2 superoxide dismutase 2, mitochondrial
TERT telomerase reverse transcriptase
TK1 thymidine kinase 1, soluble
TNF tumor necrosis factor
TNNI3 troponin I type 3 (cardiac)
TP53 tumor protein p53
TYMP thymidine phosphorylase
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
XPA xeroderma pigmentosum, complementation group A
XPC xeroderma pigmentosum, complementation group C