| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Zileuton perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Zileuton_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.138971 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.111061 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.107517 |
| PLAT | plasminogen activator, tissue | 0.103478 |
| MEF2A | myocyte enhancer factor 2A | 0.0742848 |
| FMN1 | formin 1 | 0.0733857 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0730391 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.072169 |
| MAP1B | microtubule-associated protein 1B | 0.0715058 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0645604 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0614716 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0602262 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0597699 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0590349 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0512285 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0482019 |
| VMP1 | vacuole membrane protein 1 | 0.0476413 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0443149 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0413756 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.041232 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0399867 |
| DPH6 | diphthamine biosynthesis 6 | 0.0396478 |
| SYT1 | synaptotagmin I | 0.0395201 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0392159 |
| PCBP3 | poly(rC) binding protein 3 | 0.0387946 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0387231 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0382891 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0368235 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0361807 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0355695 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0353728 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.034138 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.033788 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0334021 |
| SIK2 | salt-inducible kinase 2 | 0.033307 |
| NRP1 | neuropilin 1 | 0.0328217 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0326183 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0325526 |
| DGKH | diacylglycerol kinase, eta | 0.0321068 |
| PTEN | phosphatase and tensin homolog | 0.0316258 |
| SEPTIN9 | septin 9 | 0.0310843 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0310229 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0299918 |
| ATRNL1 | attractin-like 1 | 0.0298949 |
| DNM3 | dynamin 3 | 0.0295533 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0294354 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0293317 |
| SCG2 | secretogranin II | 0.028513 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0282453 |
| ANGPT1 | angiopoietin 1 | 0.0279612 |
| NRG1 | neuregulin 1 | 0.0277996 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.027417 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0272054 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.0266616 |
| RUNX1 | runt-related transcription factor 1 | 0.0264456 |
| KLHL13 | kelch-like family member 13 | 0.026402 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0263975 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0263887 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0261843 |
| GPC5 | glypican 5 | 0.026071 |
| DNMBP | dynamin binding protein | 0.0260035 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0259237 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0259199 |
| ITGA1 | integrin, alpha 1 | 0.0257517 |
| SMYD3 | SET and MYND domain containing 3 | 0.0256585 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0255626 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0253575 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0253335 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0253258 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0251572 |
| RASGRF2 | Ras protein-specific guanine nucleotide-releasing factor 2 | 0.0245111 |
| ASPH | aspartate beta-hydroxylase | 0.0242999 |
| CTSB | cathepsin B | 0.0240664 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0240294 |
| WDR59 | WD repeat domain 59 | 0.0240036 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0232554 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0232052 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0231815 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0231 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0225069 |
| PCDH9 | protocadherin 9 | 0.0223849 |
| ANO6 | anoctamin 6 | 0.0219572 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0218265 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0216422 |
| MEIS2 | Meis homeobox 2 | 0.021439 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0214174 |
| YEATS2 | YEATS domain containing 2 | 0.0212558 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0212378 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0212243 |
| NBEA | neurobeachin | 0.0211903 |
| AHR | aryl hydrocarbon receptor | 0.0210496 |
| BPTF | bromodomain PHD finger transcription factor | 0.0209884 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0208377 |
| SMAD3 | SMAD family member 3 | 0.0207555 |
| GPC6 | glypican 6 | 0.0205384 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0203825 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0202962 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.020258 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0200811 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0197293 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.111477 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.106725 |
| LPIN1 | lipin 1 | -0.0917651 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0900769 |
| VCL | vinculin | -0.0705973 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.063991 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.061017 |
| RPL23 | ribosomal protein L23 | -0.0605067 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0548837 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0519126 |
| LMNA | lamin A/C | -0.0515294 |
| TRIB2 | tribbles pseudokinase 2 | -0.0493758 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0480873 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0457378 |
| LSAMP | limbic system-associated membrane protein | -0.04256 |
| HMGB2 | high mobility group box 2 | -0.0425047 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0424021 |
| RPL38 | ribosomal protein L38 | -0.0393205 |
| SQSTM1 | sequestosome 1 | -0.0390044 |
| COL3A1 | collagen, type III, alpha 1 | -0.038984 |
| RPL19 | ribosomal protein L19 | -0.0379482 |
| RPS6 | ribosomal protein S6 | -0.0365204 |
| ACTG1 | actin gamma 1 | -0.036218 |
| ENAH | enabled homolog (Drosophila) | -0.034893 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0348035 |
| CENPF | centromere protein F, 350/400kDa | -0.0346657 |
| QKI | QKI, KH domain containing, RNA binding | -0.034189 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0340048 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0333047 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0326438 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0321438 |
| SPAG9 | sperm associated antigen 9 | -0.0318706 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.031462 |
| CCDC47 | coiled-coil domain containing 47 | -0.0314029 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0308381 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0304011 |
| MED13 | mediator complex subunit 13 | -0.0303143 |
| KIF5B | kinesin family member 5B | -0.0300918 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0298853 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0292633 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.029108 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0288624 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0288355 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0286591 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.027893 |
| ZNF292 | zinc finger protein 292 | -0.0273587 |
| RPS24 | ribosomal protein S24 | -0.0266644 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0266443 |
| HELZ | helicase with zinc finger | -0.0264562 |
| SEPTIN7 | septin 7 | -0.0262223 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0260005 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0257817 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0257709 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0257167 |
| RYBP | RING1 and YY1 binding protein | -0.0254352 |
| HDLBP | high density lipoprotein binding protein | -0.0251207 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0251124 |
| RPLP1 | ribosomal protein, large, P1 | -0.0247046 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0246709 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0246398 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0240503 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0238455 |
| FRMD4A | FERM domain containing 4A | -0.0235224 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | -0.0234792 |
| RTN3 | reticulon 3 | -0.0233782 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0233082 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.023158 |
| EGR1 | early growth response 1 | -0.0231011 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0230966 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0230288 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0228183 |
| SETD5 | SET domain containing 5 | -0.0228113 |
| FOXK2 | forkhead box K2 | -0.0226248 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0225384 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0223646 |
| RPS12 | ribosomal protein S12 | -0.0222913 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0222743 |
| OGA | O-GlcNAcase | -0.0222071 |
| SUCO | SUN domain containing ossification factor | -0.0219573 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0219399 |
| NPR2 | natriuretic peptide receptor 2 | -0.0218571 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0215539 |
| GNAS | GNAS complex locus | -0.0213436 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0212247 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.0211435 |
| TPM1 | tropomyosin 1 (alpha) | -0.0209395 |
| INTS6 | integrator complex subunit 6 | -0.0208173 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.020817 |
| MORF4L2 | mortality factor 4 like 2 | -0.020806 |
| MATR3 | matrin 3 | -0.0207636 |
| RIOK3 | RIO kinase 3 | -0.0206893 |
| HMGB1 | high mobility group box 1 | -0.0206741 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0206155 |
| RLF | rearranged L-myc fusion | -0.0205456 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0203093 |
| MAP4 | microtubule-associated protein 4 | -0.0202884 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0200611 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0200494 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0199217 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0198417 |
