| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Zileuton perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Zileuton_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.169326 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.134962 |
| DOCK5 | dedicator of cytokinesis 5 | 0.133087 |
| LMO7 | LIM domain 7 | 0.131795 |
| MYOF | myoferlin | 0.109081 |
| FOXO1 | forkhead box O1 | 0.108541 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.10272 |
| BCL2L1 | BCL2-like 1 | 0.0996935 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0967774 |
| VCL | vinculin | 0.0900155 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0893281 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0859262 |
| AHNAK | AHNAK nucleoprotein | 0.0853533 |
| CD44 | CD44 molecule (Indian blood group) | 0.0783723 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.076477 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0746741 |
| ITGA6 | integrin, alpha 6 | 0.0744675 |
| PODXL | podocalyxin-like | 0.0716686 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0711697 |
| RASAL2 | RAS protein activator like 2 | 0.069983 |
| CAPRIN2 | caprin family member 2 | 0.069206 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0691021 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.068138 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0649501 |
| NDRG1 | N-myc downstream regulated 1 | 0.0613247 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0612114 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0602787 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0585885 |
| MTSS1 | metastasis suppressor 1 | 0.057095 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0570476 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0553154 |
| CUL4B | cullin 4B | 0.0548867 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0548191 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0541441 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0536752 |
| LUZP1 | leucine zipper protein 1 | 0.0532881 |
| PALLD | palladin, cytoskeletal associated protein | 0.0529256 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0517518 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0507788 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0496305 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0494259 |
| TXNIP | thioredoxin interacting protein | 0.0471253 |
| SEPTIN9 | septin 9 | 0.0468353 |
| RAI14 | retinoic acid induced 14 | 0.0465644 |
| MSN | moesin | 0.0465215 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0464325 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0458558 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0455397 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0452614 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0452106 |
| CDK6 | cyclin-dependent kinase 6 | 0.04512 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0445027 |
| DST | dystonin | 0.0435131 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0432724 |
| MCL1 | myeloid cell leukemia 1 | 0.0432267 |
| NEK7 | NIMA-related kinase 7 | 0.0430524 |
| FN1 | fibronectin 1 | 0.0424313 |
| H1-0 | H1.0 linker histone | 0.0416033 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0410814 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0403649 |
| EXT1 | exostosin glycosyltransferase 1 | 0.040027 |
| LDHA | lactate dehydrogenase A | 0.0396135 |
| KIAA1671 | KIAA1671 | 0.0391977 |
| RAB10 | RAB10, member RAS oncogene family | 0.0390095 |
| PLAT | plasminogen activator, tissue | 0.0388408 |
| SETX | senataxin | 0.0387406 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0386295 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0382836 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0382489 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0375447 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0374195 |
| CLIC4 | chloride intracellular channel 4 | 0.0373253 |
| EFNB2 | ephrin-B2 | 0.0372403 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0371214 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0367984 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0363083 |
| DUSP6 | dual specificity phosphatase 6 | 0.0362978 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0359143 |
| ENO1 | enolase 1, (alpha) | 0.0357201 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0351662 |
| OSMR | oncostatin M receptor | 0.0348363 |
| PLS3 | plastin 3 | 0.0346338 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0345913 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0343829 |
| FRMD6 | FERM domain containing 6 | 0.033752 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0326586 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0318676 |
| RCOR1 | REST corepressor 1 | 0.0317806 |
| MT2A | metallothionein 2A | 0.031678 |
| METTL15 | methyltransferase like 15 | 0.0316308 |
| VMP1 | vacuole membrane protein 1 | 0.031604 |
| DGKH | diacylglycerol kinase, eta | 0.0311866 |
| MECOM | MDS1 and EVI1 complex locus | 0.0308678 |
| ANO6 | anoctamin 6 | 0.0308638 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.030785 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0305993 |
| AOPEP | aminopeptidase O (putative) | 0.0304137 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0302666 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0300716 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0298121 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.0534316 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0466471 |
| RPS6 | ribosomal protein S6 | -0.0445736 |
| KIAA1217 | KIAA1217 | -0.0425283 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.041706 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0395076 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0346115 |
| RPS8 | ribosomal protein S8 | -0.0334513 |
| B2M | beta-2-microglobulin | -0.0327208 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0290873 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.027828 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0270859 |
| RPL37A | ribosomal protein L37a | -0.0257826 |
| HLA-B | major histocompatibility complex, class I, B | -0.0256487 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0254026 |
| RPS21 | ribosomal protein S21 | -0.0250097 |
| RPS2 | ribosomal protein S2 | -0.0249377 |
| RPS12 | ribosomal protein S12 | -0.0249306 |
| SQSTM1 | sequestosome 1 | -0.0246517 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0245439 |
| OGA | O-GlcNAcase | -0.0240881 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0240267 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0239694 |
| PTK2 | protein tyrosine kinase 2 | -0.0236845 |
| GOLGA4 | golgin A4 | -0.0236591 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0235337 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0234366 |
| STC1 | stanniocalcin 1 | -0.0234283 |
| MATR3 | matrin 3 | -0.0234158 |
| RPS3 | ribosomal protein S3 | -0.0233921 |
| DSTN | destrin (actin depolymerizing factor) | -0.0233875 |
| RPL34 | ribosomal protein L34 | -0.0232655 |
| RBM39 | RNA binding motif protein 39 | -0.0230458 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0226207 |
| RPL37 | ribosomal protein L37 | -0.0218914 |
| NUP58 | nucleoporin 58 | -0.0216581 |
| RLF | rearranged L-myc fusion | -0.0212957 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0212778 |
| RPL35A | ribosomal protein L35a | -0.0208073 |
| RPS24 | ribosomal protein S24 | -0.020323 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.020128 |
| CANX | calnexin | -0.0201013 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0199449 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0198227 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0197169 |
| ANKRD10 | ankyrin repeat domain 10 | -0.019513 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.019465 |
| TFG | TRK-fused gene | -0.0187743 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0186719 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0184659 |
| RPL26 | ribosomal protein L26 | -0.0181094 |
| IRF1 | interferon regulatory factor 1 | -0.0179582 |
| PHF21A | PHD finger protein 21A | -0.0177928 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0176713 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0175011 |
| HLA-A | major histocompatibility complex, class I, A | -0.017491 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0173727 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0171969 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0170339 |
| FOSL1 | FOS-like antigen 1 | -0.0170204 |
| SPAG9 | sperm associated antigen 9 | -0.016883 |
| SDC4 | syndecan 4 | -0.0166869 |
| HELZ | helicase with zinc finger | -0.0166643 |
| RPS29 | ribosomal protein S29 | -0.0165297 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0164582 |
| RPL23 | ribosomal protein L23 | -0.0164157 |
| NOP58 | NOP58 ribonucleoprotein | -0.0163323 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.016261 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0160119 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0159575 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.015948 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0157883 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0157703 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0157229 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0156793 |
| RPL9 | ribosomal protein L9 | -0.0155926 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0155704 |
| SUCO | SUN domain containing ossification factor | -0.0154296 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0153814 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0153351 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0153072 |
| CALR | calreticulin | -0.0151227 |
| UPP1 | uridine phosphorylase 1 | -0.0149301 |
| FUS | FUS RNA binding protein | -0.0148356 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0148287 |
| USP3 | ubiquitin specific peptidase 3 | -0.0148239 |
| RPS27A | ribosomal protein S27a | -0.0147838 |
| GLRX3 | glutaredoxin 3 | -0.0145548 |
| PPA1 | pyrophosphatase (inorganic) 1 | -0.0144468 |
| GTF2B | general transcription factor IIB | -0.0143935 |
| MXD1 | MAX dimerization protein 1 | -0.0143339 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0142729 |
| KDM1A | lysine (K)-specific demethylase 1A | -0.0142267 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0142183 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0141654 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.014115 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | -0.0140539 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0140016 |
| SEPTIN7 | septin 7 | -0.0139521 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.0139405 |
