| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Zileuton perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Zileuton_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.065854 |
| CAPRIN2 | caprin family member 2 | 0.0583186 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0565346 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0431232 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0417276 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0416538 |
| DST | dystonin | 0.0414353 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0406468 |
| VMP1 | vacuole membrane protein 1 | 0.0363841 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0345815 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0311902 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0280124 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0278995 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0275983 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0267452 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.02545 |
| F2R | coagulation factor II (thrombin) receptor | 0.0249767 |
| FNIP1 | folliculin interacting protein 1 | 0.0249454 |
| VCL | vinculin | 0.0247728 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0219993 |
| TXNRD1 | thioredoxin reductase 1 | 0.0209341 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0208401 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0208362 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0205599 |
| PRELID2 | PRELI domain containing 2 | 0.0204946 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0203191 |
| USP12 | ubiquitin specific peptidase 12 | 0.0192965 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0191093 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0190498 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0184391 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0183567 |
| ANKRD36 | ankyrin repeat domain 36 | 0.01785 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0174121 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0170513 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0166872 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0165665 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0157811 |
| RAD51B | RAD51 paralog B | 0.0157335 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.015711 |
| USP34 | ubiquitin specific peptidase 34 | 0.0155387 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0152514 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0146719 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0145212 |
| EREG | epiregulin | 0.0144512 |
| PYGL | phosphorylase, glycogen, liver | 0.0142703 |
| BARX2 | BARX homeobox 2 | 0.0139007 |
| ARRDC3 | arrestin domain containing 3 | 0.0135628 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0135307 |
| RTTN | rotatin | 0.0132774 |
| HPCAL1 | hippocalcin-like 1 | 0.0132682 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.013126 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0131069 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.012909 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0123723 |
| ANGPTL4 | angiopoietin-like 4 | 0.0122993 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0122226 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0121995 |
| SMAD3 | SMAD family member 3 | 0.01209 |
| KIAA1958 | KIAA1958 | 0.0118246 |
| RPL4 | ribosomal protein L4 | 0.0117981 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.011789 |
| CEP170 | centrosomal protein 170kDa | 0.011487 |
| ARFGEF3 | ARFGEF family member 3 | 0.0112827 |
| RPL3 | ribosomal protein L3 | 0.01128 |
| SDC4 | syndecan 4 | 0.0112558 |
| SVIL | supervillin | 0.0112552 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0111442 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0109752 |
| PDE10A | phosphodiesterase 10A | 0.0109598 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0109147 |
| FHIT | fragile histidine triad | 0.0108824 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0108235 |
| PRKCE | protein kinase C, epsilon | 0.0107712 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0106064 |
| SMYD3 | SET and MYND domain containing 3 | 0.0106039 |
| USP47 | ubiquitin specific peptidase 47 | 0.0103417 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0103028 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0102113 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0102101 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.010175 |
| EMP1 | epithelial membrane protein 1 | 0.0100633 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | 0.00990024 |
| SOCS6 | suppressor of cytokine signaling 6 | 0.00985665 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.00983399 |
| STXBP1 | syntaxin binding protein 1 | 0.0097119 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.00965237 |
| ATP13A3 | ATPase type 13A3 | 0.00963423 |
| RAB27B | RAB27B, member RAS oncogene family | 0.00962665 |
| ANO6 | anoctamin 6 | 0.00959439 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.00956041 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0094948 |
| POTEF | POTE ankyrin domain family, member F | 0.00947939 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.00940118 |
| IL6ST | interleukin 6 signal transducer | 0.0093305 |
| ANTXR2 | anthrax toxin receptor 2 | 0.00932388 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.00930758 |
| AREG | amphiregulin | 0.00906346 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.00906142 |
| ZNF638 | zinc finger protein 638 | 0.00897696 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.00897125 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.189321 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.17157 |
| PTMA | prothymosin, alpha | -0.160753 |
| VIM | vimentin | -0.142916 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0951567 |
| TMSB10 | thymosin beta 10 | -0.080205 |
| TMSB4X | thymosin beta 4, X-linked | -0.0694179 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0612665 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0519235 |
| FTL | ferritin, light polypeptide | -0.0506997 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0479304 |
| CANX | calnexin | -0.0458193 |
| RPS8 | ribosomal protein S8 | -0.0457736 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0450161 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0441631 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0422556 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0383812 |
| RPS6 | ribosomal protein S6 | -0.037289 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0355818 |
| ACTG1 | actin gamma 1 | -0.0350923 |
| CD44 | CD44 molecule (Indian blood group) | -0.0341502 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0339317 |
| CALR | calreticulin | -0.0330794 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0330304 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0329418 |
| GOLGA4 | golgin A4 | -0.0324842 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0314623 |
| RPL35A | ribosomal protein L35a | -0.0314587 |
| PGK1 | phosphoglycerate kinase 1 | -0.0310075 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0303113 |
| TFRC | transferrin receptor | -0.0300047 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0296235 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0295389 |
| HDLBP | high density lipoprotein binding protein | -0.0286505 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0280615 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0269968 |
| HMGA1 | high mobility group AT-hook 1 | -0.0268631 |
| SEPTIN7 | septin 7 | -0.02643 |
| RBM39 | RNA binding motif protein 39 | -0.0263317 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0257051 |
| RPS3 | ribosomal protein S3 | -0.0248727 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0247806 |
| CADM2 | cell adhesion molecule 2 | -0.0247374 |
| TMEM123 | transmembrane protein 123 | -0.0245765 |
| RPL19 | ribosomal protein L19 | -0.0239597 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0238681 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0238194 |
| GNAS | GNAS complex locus | -0.0238023 |
| RAI1 | retinoic acid induced 1 | -0.0236824 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.022874 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0228472 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0227588 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0222569 |
| EPHA4 | EPH receptor A4 | -0.0219621 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0216357 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0215841 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0211113 |
| RACK1 | receptor for activated C kinase 1 | -0.0208461 |
| RPL23 | ribosomal protein L23 | -0.020825 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0206646 |
| MORF4L2 | mortality factor 4 like 2 | -0.0205266 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.020319 |
| ANXA1 | annexin A1 | -0.0203055 |
| MT2A | metallothionein 2A | -0.0202828 |
| APP | amyloid beta (A4) precursor protein | -0.020249 |
| RPL12 | ribosomal protein L12 | -0.0200767 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0200323 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0199983 |
| RPL8 | ribosomal protein L8 | -0.0199451 |
| FAM162A | family with sequence similarity 162, member A | -0.0197895 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0196176 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0194738 |
| RLF | rearranged L-myc fusion | -0.0193798 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0192309 |
| YBX1 | Y box binding protein 1 | -0.0192247 |
| RBM25 | RNA binding motif protein 25 | -0.019186 |
| CAVIN1 | caveolae associated protein 1 | -0.0190853 |
| TPI1 | triosephosphate isomerase 1 | -0.0189867 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0189507 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0188736 |
| AHNAK | AHNAK nucleoprotein | -0.0188408 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.018837 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.018781 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0186597 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.018467 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0183609 |
| RPS27A | ribosomal protein S27a | -0.0183606 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.01832 |
| RPLP1 | ribosomal protein, large, P1 | -0.0180734 |
| ANXA2 | annexin A2 | -0.0179909 |
| SET | SET nuclear proto-oncogene | -0.0179801 |
| RPL37A | ribosomal protein L37a | -0.017969 |
| RIOK3 | RIO kinase 3 | -0.0177236 |
| RPL5 | ribosomal protein L5 | -0.0175288 |
| RPS24 | ribosomal protein S24 | -0.0175119 |
| PKM | pyruvate kinase, muscle | -0.017492 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0174882 |
| NOP58 | NOP58 ribonucleoprotein | -0.0174089 |
| RPL11 | ribosomal protein L11 | -0.0173861 |
| LDHA | lactate dehydrogenase A | -0.0173582 |
