| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Zileuton perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Zileuton_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.0882885 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0767443 |
| KRT17 | keratin 17, type I | 0.0736317 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0623592 |
| SBF2 | SET binding factor 2 | 0.0620203 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0566768 |
| RPS6 | ribosomal protein S6 | 0.0539353 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.053535 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0526095 |
| EZR | ezrin | 0.0427804 |
| FLNB | filamin B, beta | 0.0423341 |
| MEF2A | myocyte enhancer factor 2A | 0.0418308 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0411174 |
| ZNF207 | zinc finger protein 207 | 0.040464 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0373018 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0372959 |
| RPS12 | ribosomal protein S12 | 0.0351476 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.035125 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0342103 |
| RPL12 | ribosomal protein L12 | 0.0339133 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0336774 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.033405 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0325876 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.0325619 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0318351 |
| NAV2 | neuron navigator 2 | 0.0315831 |
| FAM13A | family with sequence similarity 13, member A | 0.0314105 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0311171 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0305824 |
| MT2A | metallothionein 2A | 0.0303064 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.03009 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0300697 |
| NEK7 | NIMA-related kinase 7 | 0.0297849 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0294553 |
| ANXA1 | annexin A1 | 0.0294148 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0291721 |
| MATR3 | matrin 3 | 0.0288218 |
| MCL1 | myeloid cell leukemia 1 | 0.028712 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0284831 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0281371 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0281132 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0279441 |
| SLTM | SAFB-like, transcription modulator | 0.0278981 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0275258 |
| SPAG9 | sperm associated antigen 9 | 0.0273392 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0271428 |
| RPS20 | ribosomal protein S20 | 0.0271025 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0268413 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0268254 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0267145 |
| ZNF292 | zinc finger protein 292 | 0.0266742 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0265286 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0265165 |
| DSPP | dentin sialophosphoprotein | 0.0258066 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0257659 |
| PCBP2 | poly(rC) binding protein 2 | 0.0254721 |
| TPM3 | tropomyosin 3 | 0.0252034 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0251742 |
| CDK6 | cyclin-dependent kinase 6 | 0.0251247 |
| CNKSR3 | CNKSR family member 3 | 0.0250892 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0249568 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0245609 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0244532 |
| RPL4 | ribosomal protein L4 | 0.0243433 |
| GPHN | gephyrin | 0.0242721 |
| ATXN1 | ataxin 1 | 0.0242289 |
| RPL31 | ribosomal protein L31 | 0.0238231 |
| JMJD1C | jumonji domain containing 1C | 0.0230514 |
| RPL35A | ribosomal protein L35a | 0.0229937 |
| RPS27A | ribosomal protein S27a | 0.0229762 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0224476 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0221474 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0220895 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0220295 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.021971 |
| SRPK2 | SRSF protein kinase 2 | 0.0219229 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0218303 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0217167 |
| MUC16 | mucin 16, cell surface associated | 0.0215039 |
| NOP58 | NOP58 ribonucleoprotein | 0.0212431 |
| PHF3 | PHD finger protein 3 | 0.0212284 |
| RNF24 | ring finger protein 24 | 0.0210768 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0210564 |
| MED12 | mediator complex subunit 12 | 0.0210282 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.020897 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0206377 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0205713 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0205637 |
| HBP1 | HMG-box transcription factor 1 | 0.020486 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0203232 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0203187 |
| RPS8 | ribosomal protein S8 | 0.0202248 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0200364 |
| FAM168B | family with sequence similarity 168, member B | 0.0200322 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0198664 |
| TPR | translocated promoter region, nuclear basket protein | 0.0198184 |
| RPS5 | ribosomal protein S5 | 0.019778 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.019771 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0197017 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0196496 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.122998 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0991236 |
| LMO7 | LIM domain 7 | -0.0689098 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0683484 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0563364 |
| PRELID2 | PRELI domain containing 2 | -0.0529245 |
| FN1 | fibronectin 1 | -0.0519869 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0509356 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0509054 |
| MYO1E | myosin IE | -0.0492106 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0484559 |
| TXNIP | thioredoxin interacting protein | -0.0481496 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0459277 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0458325 |
| SMYD3 | SET and MYND domain containing 3 | -0.0450646 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.045037 |
| DSG2 | desmoglein 2 | -0.0440997 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.04322 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0429797 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0425746 |
| PRSS23 | protease, serine, 23 | -0.0399585 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0398023 |
| AHNAK | AHNAK nucleoprotein | -0.0397647 |
| NEBL | nebulette | -0.0397352 |
| GRAMD1B | GRAM domain containing 1B | -0.0383937 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0380606 |
| ATOSA | atos homolog A | -0.0371578 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0370492 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0367588 |
| NBEA | neurobeachin | -0.0359358 |
| RNF213 | ring finger protein 213 | -0.0354528 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0353803 |
| HOOK3 | hook microtubule-tethering protein 3 | -0.0352283 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0348564 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0346672 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0341262 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0339784 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0339632 |
| ABHD17C | abhydrolase domain containing 17C | -0.0330621 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0327482 |
| CCNI | cyclin I | -0.0325075 |
| KIAA1217 | KIAA1217 | -0.0316067 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0315754 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0312355 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0306757 |
| RORA | RAR-related orphan receptor A | -0.0306666 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0303536 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0303192 |
| GLIS3 | GLIS family zinc finger 3 | -0.0301563 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0300736 |
| ZNF217 | zinc finger protein 217 | -0.0296492 |
| FOXP1 | forkhead box P1 | -0.0290956 |
| USP53 | ubiquitin specific peptidase 53 | -0.0287699 |
| BPTF | bromodomain PHD finger transcription factor | -0.0286456 |
| INHBA | inhibin, beta A | -0.0279442 |
| GOLGB1 | golgin B1 | -0.02794 |
| RUFY1 | RUN and FYVE domain containing 1 | -0.0276807 |
| FOXO1 | forkhead box O1 | -0.0274312 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0273183 |
| CDK12 | cyclin-dependent kinase 12 | -0.0271638 |
| VCAN | versican | -0.0270067 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0265353 |
| RIGI | RNA sensor RIG-I | -0.0264223 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0263471 |
| TMEM41B | transmembrane protein 41B | -0.0263151 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0263151 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0263063 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0262008 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0261183 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0260722 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0260153 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0258363 |
| TMEM87A | transmembrane protein 87A | -0.0257778 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0256623 |
| TNPO1 | transportin 1 | -0.0254272 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0253824 |
| OSMR | oncostatin M receptor | -0.0251714 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0251085 |
| ANXA2 | annexin A2 | -0.0246802 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0244208 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0244048 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0243286 |
| ZNF638 | zinc finger protein 638 | -0.0242997 |
| CEP350 | centrosomal protein 350kDa | -0.0239165 |
| CD2AP | CD2-associated protein | -0.0236629 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0236549 |
| S100A10 | S100 calcium binding protein A10 | -0.0233739 |
| DENND1A | DENN/MADD domain containing 1A | -0.023339 |
| TBC1D14 | TBC1 domain family, member 14 | -0.0225229 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0223383 |
| PLS3 | plastin 3 | -0.0222769 |
| BBX | bobby sox homolog (Drosophila) | -0.0222676 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0222294 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0217132 |
| FMN1 | formin 1 | -0.0216409 |
| ARF1 | ADP-ribosylation factor 1 | -0.0215949 |
| CUX1 | cut-like homeobox 1 | -0.0215647 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0215054 |
| AK1 | adenylate kinase 1 | -0.0214899 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0213579 |
