| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Zileuton perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Zileuton_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0851718 |
| HDAC9 | histone deacetylase 9 | 0.0695886 |
| SPAG9 | sperm associated antigen 9 | 0.0634883 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0631374 |
| ZNF292 | zinc finger protein 292 | 0.0631151 |
| ZNF608 | zinc finger protein 608 | 0.0602011 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0566185 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0561493 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0555203 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0476318 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0465934 |
| PDGFC | platelet derived growth factor C | 0.0455687 |
| TENM3 | teneurin transmembrane protein 3 | 0.0447296 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0434251 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0429214 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0427708 |
| DST | dystonin | 0.0421512 |
| FIGN | fidgetin | 0.0413898 |
| ECT2 | epithelial cell transforming 2 | 0.0404169 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0401004 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.039577 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0392984 |
| CDC73 | cell division cycle 73 | 0.0384219 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0375072 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0368382 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0366843 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0348585 |
| METAP2 | methionyl aminopeptidase 2 | 0.0330034 |
| SHROOM3 | shroom family member 3 | 0.0326793 |
| ZNF385D | zinc finger protein 385D | 0.0319767 |
| MED13L | mediator complex subunit 13-like | 0.0310203 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0309714 |
| RBM20 | RNA binding motif protein 20 | 0.030641 |
| ZNF217 | zinc finger protein 217 | 0.0304594 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0294814 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0290728 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0288852 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0273255 |
| ANXA5 | annexin A5 | 0.0272333 |
| ARHGAP15 | Rho GTPase activating protein 15 | 0.0255764 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.0242731 |
| ANK2 | ankyrin 2, neuronal | 0.0242375 |
| FAM171B | family with sequence similarity 171, member B | 0.023962 |
| PHF3 | PHD finger protein 3 | 0.023918 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0238215 |
| KIF4A | kinesin family member 4A | 0.023773 |
| RASAL2 | RAS protein activator like 2 | 0.0237231 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.023608 |
| PGPEP1L | pyroglutamyl-peptidase I-like | 0.0234835 |
| BNC2 | basonuclin 2 | 0.0233638 |
| TRERF1 | transcriptional regulating factor 1 | 0.0233602 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0228759 |
| H1-4 | H1.4 linker histone, cluster member | 0.0228173 |
| CEP192 | centrosomal protein 192kDa | 0.02277 |
| CCNA2 | cyclin A2 | 0.0227191 |
| ABI2 | abl-interactor 2 | 0.0226053 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0225943 |
| TENM2 | teneurin transmembrane protein 2 | 0.0225785 |
| WDR43 | WD repeat domain 43 | 0.0223472 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0220001 |
| EVI5 | ecotropic viral integration site 5 | 0.0219735 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0219492 |
| STRN | striatin, calmodulin binding protein | 0.0218729 |
| PEG10 | paternally expressed 10 | 0.0218152 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.0217269 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0216561 |
| MB21D2 | Mab-21 domain containing 2 | 0.0213796 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0213545 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0213037 |
| TLK2 | tousled-like kinase 2 | 0.0212118 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0210381 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0209126 |
| MAPK1 | mitogen-activated protein kinase 1 | 0.0208644 |
| ACBD6 | acyl-CoA binding domain containing 6 | 0.020838 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0207156 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0206748 |
| PGRMC1 | progesterone receptor membrane component 1 | 0.0206247 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.020371 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0202867 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0200226 |
| GPC4 | glypican 4 | 0.0197676 |
| TOX | thymocyte selection-associated high mobility group box | 0.0197568 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0196605 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.0196582 |
| TTK | TTK protein kinase | 0.0196159 |
| TMSB4X | thymosin beta 4, X-linked | 0.0195446 |
| GASK1B | golgi associated kinase 1B | 0.0194878 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0189505 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0188585 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0186313 |
| RNF13 | ring finger protein 13 | 0.0186172 |
| TMEM64 | transmembrane protein 64 | 0.0185958 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0185481 |
| RBM26 | RNA binding motif protein 26 | 0.0183658 |
| MEMO1 | mediator of cell motility 1 | 0.0183333 |
| RHEB | Ras homolog enriched in brain | 0.0183297 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0179967 |
| TMF1 | TATA element modulatory factor 1 | 0.0179832 |
| PLPP1 | phospholipid phosphatase 1 | 0.0179499 |
| CDC14A | cell division cycle 14A | 0.0179244 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.221737 |
| PTMA | prothymosin, alpha | -0.15182 |
| COL11A1 | collagen, type XI, alpha 1 | -0.149595 |
| TMSB10 | thymosin beta 10 | -0.140543 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.128887 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.119243 |
| RPS16 | ribosomal protein S16 | -0.0975698 |
| RPS6 | ribosomal protein S6 | -0.0826984 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0821373 |
| RPS8 | ribosomal protein S8 | -0.0814772 |
| PCDH9 | protocadherin 9 | -0.0716327 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0702291 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0668522 |
| CALR | calreticulin | -0.062784 |
| PGK1 | phosphoglycerate kinase 1 | -0.0617829 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0604345 |
| ENO1 | enolase 1, (alpha) | -0.0595838 |
| RPL23 | ribosomal protein L23 | -0.0559524 |
| RPLP1 | ribosomal protein, large, P1 | -0.0542647 |
| NTM | neurotrimin | -0.0540622 |
| FN1 | fibronectin 1 | -0.05402 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0532418 |
| RPS12 | ribosomal protein S12 | -0.0528509 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0509734 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0504342 |
| RPS27A | ribosomal protein S27a | -0.0501288 |
| SNX6 | sorting nexin 6 | -0.0499941 |
| COL1A2 | collagen, type I, alpha 2 | -0.049949 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0493105 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.046958 |
| RPL35A | ribosomal protein L35a | -0.0463881 |
| RPL37A | ribosomal protein L37a | -0.0460623 |
| CADM2 | cell adhesion molecule 2 | -0.0459754 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0445857 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0426151 |
| GNAS | GNAS complex locus | -0.0416249 |
| RPS19 | ribosomal protein S19 | -0.0415926 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0407701 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0399188 |
| ACTG1 | actin gamma 1 | -0.0395321 |
| RPL11 | ribosomal protein L11 | -0.0395174 |
| S100A10 | S100 calcium binding protein A10 | -0.0385614 |
| UBC | ubiquitin C | -0.0384548 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0372675 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0371088 |
| RPLP2 | ribosomal protein, large, P2 | -0.0360387 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0355743 |
| RPL5 | ribosomal protein L5 | -0.0352569 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0351056 |
| RPS25 | ribosomal protein S25 | -0.0350881 |
| RPL32 | ribosomal protein L32 | -0.0348059 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0346996 |
| RPL37 | ribosomal protein L37 | -0.0345604 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0342522 |
| RPS21 | ribosomal protein S21 | -0.0341461 |
| YBX1 | Y box binding protein 1 | -0.0341099 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0337663 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0331698 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0328501 |
| AHNAK | AHNAK nucleoprotein | -0.0326231 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0325281 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0323553 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.03216 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0320367 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0309517 |
| RPL12 | ribosomal protein L12 | -0.0306919 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0301299 |
| RPS29 | ribosomal protein S29 | -0.0300462 |
| PCBP2 | poly(rC) binding protein 2 | -0.0299981 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0296533 |
| HMCN1 | hemicentin 1 | -0.0296465 |
| S100A9 | S100 calcium binding protein A9 | -0.0294947 |
| PFN1 | profilin 1 | -0.0294212 |
| RPS13 | ribosomal protein S13 | -0.0291154 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0289017 |
| CALU | calumenin | -0.0288745 |
| SBF2 | SET binding factor 2 | -0.0283538 |
| RPL38 | ribosomal protein L38 | -0.0283435 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0281443 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0278735 |
| RPS3 | ribosomal protein S3 | -0.0277952 |
| EMP1 | epithelial membrane protein 1 | -0.0277292 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0277253 |
| RPL9 | ribosomal protein L9 | -0.0276896 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0276468 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0276151 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0272837 |
| SQSTM1 | sequestosome 1 | -0.02707 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0268645 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0267004 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0265038 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0263345 |
| RPL7 | ribosomal protein L7 | -0.0262294 |
| SET | SET nuclear proto-oncogene | -0.0262266 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0260659 |
| LDHA | lactate dehydrogenase A | -0.026063 |
| HMGB1 | high mobility group box 1 | -0.0259482 |
| RPL30 | ribosomal protein L30 | -0.0259469 |
| STMN1 | stathmin 1 | -0.0258383 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0258324 |
