| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Zileuton perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Zileuton_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.10274 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.10165 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0916523 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0885526 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0865347 |
| VIM | vimentin | 0.0760069 |
| ANLN | anillin, actin binding protein | 0.0673101 |
| HLA-B | major histocompatibility complex, class I, B | 0.0650352 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0630487 |
| B2M | beta-2-microglobulin | 0.0630069 |
| STC1 | stanniocalcin 1 | 0.0595303 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0568502 |
| CENPE | centromere protein E, 312kDa | 0.0544012 |
| WASF2 | WAS protein family, member 2 | 0.0465841 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0464298 |
| NAV2 | neuron navigator 2 | 0.0450675 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0445711 |
| SSH1 | slingshot protein phosphatase 1 | 0.0405797 |
| ERBIN | erbb2 interacting protein | 0.0402974 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0395781 |
| JMJD1C | jumonji domain containing 1C | 0.0391028 |
| CENPF | centromere protein F, 350/400kDa | 0.0381293 |
| POTEF | POTE ankyrin domain family, member F | 0.0377734 |
| HLA-A | major histocompatibility complex, class I, A | 0.0375887 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0367124 |
| IL6 | interleukin 6 | 0.0363434 |
| MKI67 | marker of proliferation Ki-67 | 0.0358568 |
| UBC | ubiquitin C | 0.0354155 |
| GOLGA4 | golgin A4 | 0.0353507 |
| MATR3 | matrin 3 | 0.0339539 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0333134 |
| TPX2 | TPX2, microtubule-associated | 0.0324682 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0323568 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0320805 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0320023 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0310327 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0305069 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0298218 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0298036 |
| CIRSR | corepressor of RBPJ and splicing regulator | 0.0288837 |
| ATP13A3 | ATPase type 13A3 | 0.028709 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0279829 |
| PGM3 | phosphoglucomutase 3 | 0.0275746 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0275468 |
| SEPTIN2 | septin 2 | 0.0274327 |
| HJURP | Holliday junction recognition protein | 0.0270278 |
| DNPEP | aspartyl aminopeptidase | 0.0268123 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0268036 |
| RACK1 | receptor for activated C kinase 1 | 0.0267373 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0263062 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0261298 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0257072 |
| ARRDC3 | arrestin domain containing 3 | 0.0251329 |
| CKAP2 | cytoskeleton associated protein 2 | 0.024579 |
| MYADM | myeloid-associated differentiation marker | 0.0245502 |
| YEATS2 | YEATS domain containing 2 | 0.0243781 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0243555 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0243338 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0242191 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0241552 |
| GOLGB1 | golgin B1 | 0.024125 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0241153 |
| TMED5 | transmembrane emp24 protein transport domain containing 5 | 0.0239038 |
| CCDC88A | coiled-coil domain containing 88A | 0.0238345 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0236901 |
| SEC24A | SEC24 family member A | 0.0232247 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0231258 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0230404 |
| BRD8 | bromodomain containing 8 | 0.0228073 |
| NKTR | natural killer cell triggering receptor | 0.0227288 |
| ANKRD36 | ankyrin repeat domain 36 | 0.022593 |
| TMEM165 | transmembrane protein 165 | 0.0225305 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0224681 |
| MTPN | myotrophin | 0.0223604 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0219633 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0218807 |
| RTN4 | reticulon 4 | 0.0217803 |
| TRRAP | transformation/transcription domain-associated protein | 0.0217741 |
| S100A10 | S100 calcium binding protein A10 | 0.0217528 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0217295 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0216642 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0216438 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0215568 |
| FOSL1 | FOS-like antigen 1 | 0.0214198 |
| KIF5B | kinesin family member 5B | 0.0211069 |
| TAPBP | TAP binding protein (tapasin) | 0.021083 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0210212 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.020987 |
| CDK19 | cyclin-dependent kinase 19 | 0.0209217 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0208606 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0208489 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0208486 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0208384 |
| LYSMD3 | LysM, putative peptidoglycan-binding, domain containing 3 | 0.0206554 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | 0.0206077 |
| PRR11 | proline rich 11 | 0.0205986 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0205457 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0204846 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0203994 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0203384 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.250295 |
| COL6A3 | collagen, type VI, alpha 3 | -0.161424 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.157161 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.128053 |
| CALD1 | caldesmon 1 | -0.105747 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0857552 |
| COL1A1 | collagen, type I, alpha 1 | -0.0844854 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0776631 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0733805 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.073099 |
| VCL | vinculin | -0.0712836 |
| NRXN3 | neurexin 3 | -0.0705484 |
| DST | dystonin | -0.0704358 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0658318 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0615481 |
| AHNAK | AHNAK nucleoprotein | -0.0613963 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0608224 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0592936 |
| CALU | calumenin | -0.0582189 |
| TMSB10 | thymosin beta 10 | -0.0565038 |
| PGK1 | phosphoglycerate kinase 1 | -0.0560276 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0546848 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.051993 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0517149 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0513646 |
| CDH13 | cadherin 13 | -0.050161 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.050006 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0499103 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0497069 |
| FN1 | fibronectin 1 | -0.0479559 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0465307 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0460935 |
| TNS3 | tensin 3 | -0.0457234 |
| KAZN | kazrin, periplakin interacting protein | -0.0456912 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0455969 |
| ACTG1 | actin gamma 1 | -0.0454721 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0452286 |
| MYOF | myoferlin | -0.0447626 |
| CADM1 | cell adhesion molecule 1 | -0.0447027 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0446745 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0435681 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0434864 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0428966 |
| GLIS3 | GLIS family zinc finger 3 | -0.0428196 |
| NDRG1 | N-myc downstream regulated 1 | -0.0427264 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0425875 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0419003 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.041329 |
| PTMA | prothymosin, alpha | -0.0404181 |
| FUS | FUS RNA binding protein | -0.0402574 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0399245 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0395319 |
| COL1A2 | collagen, type I, alpha 2 | -0.0389626 |
| CAVIN1 | caveolae associated protein 1 | -0.0383621 |
| CANX | calnexin | -0.0381694 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.0377566 |
| ADM | adrenomedullin | -0.0373243 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0372899 |
| CALR | calreticulin | -0.0371521 |
| SQSTM1 | sequestosome 1 | -0.0364862 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0362959 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0358829 |
| MEF2A | myocyte enhancer factor 2A | -0.0350355 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0349182 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0348388 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0347561 |
| GNAS | GNAS complex locus | -0.0343608 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0343255 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0338954 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.033787 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0337677 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0337578 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.033501 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0328873 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0328798 |
| TPI1 | triosephosphate isomerase 1 | -0.0327577 |
| RAD51B | RAD51 paralog B | -0.0327559 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0324851 |
| FRMD4A | FERM domain containing 4A | -0.0318439 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0317408 |
| BRD4 | bromodomain containing 4 | -0.0315004 |
| LMNA | lamin A/C | -0.0312578 |
| LOX | lysyl oxidase | -0.0310051 |
| NABP1 | nucleic acid binding protein 1 | -0.0307648 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0303706 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.029865 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0297097 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0296658 |
| ATXN1 | ataxin 1 | -0.0294683 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0293591 |
| PRKCA | protein kinase C, alpha | -0.0293299 |
| RBM39 | RNA binding motif protein 39 | -0.0292742 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0292516 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0289852 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0289009 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.028735 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0284746 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0284326 |
| ANXA2 | annexin A2 | -0.0284048 |
| TNNC1 | troponin C type 1 (slow) | -0.0282338 |
