| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Zileuton perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Zileuton_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.130906 |
| CAPRIN2 | caprin family member 2 | 0.0783571 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0649398 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0614692 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.05762 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0572227 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0548302 |
| DNER | delta/notch-like EGF repeat containing | 0.049422 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0480771 |
| RNF111 | ring finger protein 111 | 0.0478671 |
| PARD3 | par-3 family cell polarity regulator | 0.0477124 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0467721 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0438212 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0424765 |
| TCF12 | transcription factor 12 | 0.0413812 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0406254 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0387259 |
| EXOC6B | exocyst complex component 6B | 0.038673 |
| EPAS1 | endothelial PAS domain protein 1 | 0.038203 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0381546 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0374561 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0364969 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0362848 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0360981 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0358508 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0358481 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0354374 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0348897 |
| RPL4 | ribosomal protein L4 | 0.0346689 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0342494 |
| FMNL2 | formin-like 2 | 0.0341856 |
| LDHA | lactate dehydrogenase A | 0.0340992 |
| PDE8A | phosphodiesterase 8A | 0.033546 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0329518 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0325799 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.032578 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.032088 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0303414 |
| TAOK3 | TAO kinase 3 | 0.0299812 |
| CLASP2 | cytoplasmic linker associated protein 2 | 0.0295757 |
| CLASP1 | cytoplasmic linker associated protein 1 | 0.0292424 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.029196 |
| IPO11 | importin 11 | 0.0291664 |
| ATP13A3 | ATPase type 13A3 | 0.0290228 |
| RNF145 | ring finger protein 145 | 0.0289853 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0284917 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0283565 |
| NBR1 | neighbor of BRCA1 gene 1 | 0.0280327 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0278816 |
| RGS17 | regulator of G-protein signaling 17 | 0.027622 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0275303 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0272601 |
| KIAA1328 | KIAA1328 | 0.0270507 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.0270096 |
| CUL3 | cullin 3 | 0.0265509 |
| AHR | aryl hydrocarbon receptor | 0.0262993 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0262193 |
| SNX9 | sorting nexin 9 | 0.0261755 |
| ATF7IP | activating transcription factor 7 interacting protein | 0.0260537 |
| ARHGAP18 | Rho GTPase activating protein 18 | 0.0260114 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0259006 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0258311 |
| TPI1 | triosephosphate isomerase 1 | 0.0256498 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0255467 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0254591 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | 0.0252154 |
| NEK1 | NIMA-related kinase 1 | 0.0251687 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0247132 |
| PRKD1 | protein kinase D1 | 0.0246293 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0246123 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | 0.0244256 |
| RAB31 | RAB31, member RAS oncogene family | 0.0242687 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0242161 |
| GPR107 | G protein-coupled receptor 107 | 0.0241286 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0240304 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0238145 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0237566 |
| NBAS | neuroblastoma amplified sequence | 0.0237235 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0233343 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0231081 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0230568 |
| ZBTB25 | zinc finger and BTB domain containing 25 | 0.0230442 |
| ZNF407 | zinc finger protein 407 | 0.023043 |
| SNX13 | sorting nexin 13 | 0.0230195 |
| HDLBP | high density lipoprotein binding protein | 0.0227412 |
| UBE3A | ubiquitin protein ligase E3A | 0.0226993 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | 0.0226737 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0225424 |
| COPA | coatomer protein complex, subunit alpha | 0.0223751 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0223579 |
| TLK1 | tousled-like kinase 1 | 0.0222779 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0222342 |
| ZFR | zinc finger RNA binding protein | 0.0220226 |
| FAM3C | family with sequence similarity 3, member C | 0.0219794 |
| CUL5 | cullin 5 | 0.0218458 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0217203 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 0.021664 |
| HMGB1 | high mobility group box 1 | 0.0213756 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.021294 |
| CNST | consortin, connexin sorting protein | 0.0211713 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.140349 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.105134 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.102664 |
| CENPF | centromere protein F, 350/400kDa | -0.0851798 |
| SQSTM1 | sequestosome 1 | -0.0781922 |
| GOLGA4 | golgin A4 | -0.0755388 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0745507 |
| NAV2 | neuron navigator 2 | -0.0744334 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0734044 |
| ERBIN | erbb2 interacting protein | -0.0731375 |
| PTMA | prothymosin, alpha | -0.0728746 |
| SMYD3 | SET and MYND domain containing 3 | -0.071822 |
| ATM | ATM serine/threonine kinase | -0.0685463 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0669693 |
| RRBP1 | ribosome binding protein 1 | -0.0623415 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.060804 |
| LMO7 | LIM domain 7 | -0.0601922 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0599089 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0586937 |
| GOLGB1 | golgin B1 | -0.0575832 |
| RBM39 | RNA binding motif protein 39 | -0.0536892 |
| FBXO11 | F-box protein 11 | -0.0536223 |
| TPX2 | TPX2, microtubule-associated | -0.0521909 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0501621 |
| PHF20 | PHD finger protein 20 | -0.050129 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0498303 |
| YBX3 | Y box binding protein 3 | -0.048036 |
| CPNE1 | copine I | -0.0477171 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0471992 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0458037 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0458025 |
| ANLN | anillin, actin binding protein | -0.0457403 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0456073 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0452046 |
| TXNRD1 | thioredoxin reductase 1 | -0.044274 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0442737 |
| CD44 | CD44 molecule (Indian blood group) | -0.043979 |
| NF1 | neurofibromin 1 | -0.0434276 |
| CALU | calumenin | -0.0430116 |
| DEK | DEK proto-oncogene | -0.0426406 |
| CEP57 | centrosomal protein 57kDa | -0.0414551 |
| SPAG9 | sperm associated antigen 9 | -0.041368 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0382287 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0379038 |
| OGA | O-GlcNAcase | -0.0377104 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0367082 |
| SETD5 | SET domain containing 5 | -0.0365138 |
| B2M | beta-2-microglobulin | -0.0362658 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0361146 |
| RPL26 | ribosomal protein L26 | -0.0360362 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0354217 |
| RPL36 | ribosomal protein L36 | -0.0352594 |
| CEP350 | centrosomal protein 350kDa | -0.0352434 |
| LMNA | lamin A/C | -0.0350091 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0349398 |
| RPL38 | ribosomal protein L38 | -0.0346888 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.034663 |
| DENND4A | DENN/MADD domain containing 4A | -0.0343209 |
| KIF5B | kinesin family member 5B | -0.0342173 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0341522 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0341369 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0337694 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0336745 |
| S100A10 | S100 calcium binding protein A10 | -0.0336731 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0335755 |
| MT2A | metallothionein 2A | -0.0334237 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -0.032704 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0326777 |
| RBMX | RNA binding motif protein, X-linked | -0.0326469 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0325977 |
| NUP58 | nucleoporin 58 | -0.0325029 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0323831 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0315559 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0314123 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0313762 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0312304 |
| RTN4 | reticulon 4 | -0.0312132 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0311283 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0308231 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0306729 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0305045 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0303872 |
| YAP1 | Yes-associated protein 1 | -0.0300223 |
| ENO1 | enolase 1, (alpha) | -0.0300176 |
| TMEM123 | transmembrane protein 123 | -0.0298911 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0297743 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0296791 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 | -0.029566 |
| H1-0 | H1.0 linker histone | -0.0295075 |
| CCNL1 | cyclin L1 | -0.0294802 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0293063 |
| RAB10 | RAB10, member RAS oncogene family | -0.0292422 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.029232 |
| RPLP0 | ribosomal protein, large, P0 | -0.0290383 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0289322 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0288481 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0286827 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0285933 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0285222 |
| TMEM167A | transmembrane protein 167A | -0.0282887 |
