| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Zileuton perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Zileuton_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0873355 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0518793 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.043346 |
| SMOX | spermine oxidase | 0.0417753 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0322693 |
| RUNX2 | runt-related transcription factor 2 | 0.0320301 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0314429 |
| ETNK1 | ethanolamine kinase 1 | 0.0298781 |
| OSMR | oncostatin M receptor | 0.0297959 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0290235 |
| TMEM156 | transmembrane protein 156 | 0.0282796 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0281094 |
| CD109 | CD109 molecule | 0.0265318 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0263028 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0257802 |
| OGA | O-GlcNAcase | 0.0255521 |
| GLIS3 | GLIS family zinc finger 3 | 0.0248974 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0244327 |
| NRP1 | neuropilin 1 | 0.0240067 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0237893 |
| VCL | vinculin | 0.0232722 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0231128 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0229964 |
| IL6ST | interleukin 6 signal transducer | 0.0229617 |
| PELO | pelota homolog (Drosophila) | 0.022715 |
| ADD3 | adducin 3 (gamma) | 0.0224361 |
| SMAD3 | SMAD family member 3 | 0.0222669 |
| CAB39 | calcium binding protein 39 | 0.0222542 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0218985 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0215459 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0203039 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0200207 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0185918 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.018331 |
| FBXO34 | F-box protein 34 | 0.0178923 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.017806 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0175777 |
| ATP9A | ATPase, class II, type 9A | 0.0171618 |
| FAM3C | family with sequence similarity 3, member C | 0.0171318 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0170401 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0170235 |
| SSH1 | slingshot protein phosphatase 1 | 0.0164616 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0163499 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.015725 |
| PRELID2 | PRELI domain containing 2 | 0.0157162 |
| HOMER2 | homer scaffolding protein 2 | 0.015475 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0154165 |
| CD44 | CD44 molecule (Indian blood group) | 0.0152637 |
| RAB31 | RAB31, member RAS oncogene family | 0.0151738 |
| ZFHX3 | zinc finger homeobox 3 | 0.0143876 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0143527 |
| WDR26 | WD repeat domain 26 | 0.0143396 |
| CEP192 | centrosomal protein 192kDa | 0.0142234 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0140981 |
| GPC6 | glypican 6 | 0.0140918 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0139476 |
| LAMA4 | laminin, alpha 4 | 0.013682 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0135932 |
| HDAC8 | histone deacetylase 8 | 0.013577 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0135136 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 0.0135049 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0133735 |
| RCOR3 | REST corepressor 3 | 0.0133103 |
| THOC2 | THO complex 2 | 0.0132258 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.013204 |
| FAM20C | family with sequence similarity 20, member C | 0.0131413 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0130802 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.0130567 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0130197 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0129967 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0129786 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0128692 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0128683 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0128445 |
| PPARA | peroxisome proliferator-activated receptor alpha | 0.0128105 |
| ZNF146 | zinc finger protein 146 | 0.0127679 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0126952 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0126251 |
| EXOC4 | exocyst complex component 4 | 0.0125349 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0125151 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.0125054 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0124673 |
| RIC1 | RAB6A GEF complex partner 1 | 0.0124599 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0124296 |
| MSI2 | musashi RNA-binding protein 2 | 0.0124048 |
| SP3 | Sp3 transcription factor | 0.0122835 |
| SBF2 | SET binding factor 2 | 0.0122723 |
| PLPP3 | phospholipid phosphatase 3 | 0.012203 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0121821 |
| ZNF638 | zinc finger protein 638 | 0.0120888 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0120554 |
| OTUD7B | OTU deubiquitinase 7B | 0.0120054 |
| CREB1 | cAMP responsive element binding protein 1 | 0.011995 |
| RO60 | Ro60, Y RNA binding protein | 0.0119942 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0119802 |
| FRY | furry homolog (Drosophila) | 0.0119547 |
| RNF149 | ring finger protein 149 | 0.0119186 |
| PDE8A | phosphodiesterase 8A | 0.0117747 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0117565 |
| AMN1 | antagonist of mitotic exit network 1 homolog (S. cerevisiae) | 0.0117303 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.267103 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.252284 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.237945 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.203083 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.167072 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.143373 |
| NRG1 | neuregulin 1 | -0.138744 |
| PTMA | prothymosin, alpha | -0.114987 |
| SQSTM1 | sequestosome 1 | -0.110541 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0994401 |
| CANX | calnexin | -0.097567 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0876914 |
| MT2A | metallothionein 2A | -0.0857664 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0808467 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0788674 |
| S100A6 | S100 calcium binding protein A6 | -0.0772165 |
| HMGA2 | high mobility group AT-hook 2 | -0.0756304 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0752021 |
| VIM | vimentin | -0.0740522 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0702813 |
| LMNA | lamin A/C | -0.0700946 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0697141 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0660902 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0657414 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0651056 |
| ASPH | aspartate beta-hydroxylase | -0.0649043 |
| B2M | beta-2-microglobulin | -0.0632325 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0601254 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0584976 |
| ENO1 | enolase 1, (alpha) | -0.0583546 |
| FTL | ferritin, light polypeptide | -0.0581086 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0561593 |
| TMSB10 | thymosin beta 10 | -0.0560484 |
| RACK1 | receptor for activated C kinase 1 | -0.0557717 |
| TMSB4X | thymosin beta 4, X-linked | -0.0547627 |
| PLIN2 | perilipin 2 | -0.0529181 |
| RPL26 | ribosomal protein L26 | -0.0487425 |
| S100A10 | S100 calcium binding protein A10 | -0.047632 |
| SPAG9 | sperm associated antigen 9 | -0.0476309 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0440525 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0439995 |
| CALR | calreticulin | -0.0434759 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.043458 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0416479 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0410115 |
| EZR | ezrin | -0.0403344 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0388335 |
| ITGA1 | integrin, alpha 1 | -0.0385543 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0384107 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0378132 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0376531 |
| H1-0 | H1.0 linker histone | -0.0369936 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0369273 |
| RPS6 | ribosomal protein S6 | -0.0367403 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0367141 |
| RAI14 | retinoic acid induced 14 | -0.0362466 |
| HMGA1 | high mobility group AT-hook 1 | -0.0362241 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.036068 |
| ARF1 | ADP-ribosylation factor 1 | -0.0360528 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0351084 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0349903 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0348179 |
| MAP1B | microtubule-associated protein 1B | -0.0341503 |
| SFTPA2 | surfactant protein A2 | -0.0335948 |
| DSTN | destrin (actin depolymerizing factor) | -0.0334655 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0333542 |
| GNAS | GNAS complex locus | -0.0332337 |
| SYT1 | synaptotagmin I | -0.0330794 |
| RPS27 | ribosomal protein S27 | -0.0328036 |
| HLA-B | major histocompatibility complex, class I, B | -0.0323451 |
| EMP1 | epithelial membrane protein 1 | -0.0320645 |
| STC2 | stanniocalcin 2 | -0.0318562 |
| CALU | calumenin | -0.0316658 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0316288 |
| RPL37A | ribosomal protein L37a | -0.0315528 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0314925 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0314262 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0312227 |
| NOP58 | NOP58 ribonucleoprotein | -0.0311363 |
| IER3 | immediate early response 3 | -0.0310952 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0310025 |
| JUN | jun proto-oncogene | -0.0309842 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0307297 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0304743 |
| ATF3 | activating transcription factor 3 | -0.0304509 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.030238 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0301441 |
| SEPTIN7 | septin 7 | -0.0298218 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0297914 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0296685 |
| RND3 | Rho family GTPase 3 | -0.0295092 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0292964 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0292911 |
| SON | SON DNA binding protein | -0.0292367 |
| CENPF | centromere protein F, 350/400kDa | -0.0287083 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.028687 |
| RPLP1 | ribosomal protein, large, P1 | -0.0286176 |
| RPS12 | ribosomal protein S12 | -0.0279423 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0279251 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0279219 |
