Zollinger-Ellison Syndrome Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A syndrome that is haracterized by the development of a one or more tumors (gastrinoma) in the pancreas, duodenum, or both that secrete excessive levels of gastrin, a hormone that stimulates production of acid by the stomach. (Human Disease Ontology, DOID_0050782)
External Link https://www.disgenet.org/browser/0/1/0/C0043515
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Genes

20 genes associated with the disease Zollinger-Ellison Syndrome in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ATRX alpha thalassemia/mental retardation syndrome X-linked
CCKBR cholecystokinin B receptor
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CHGA chromogranin A
CXCL8 chemokine (C-X-C motif) ligand 8
DAXX death-domain associated protein
GAST gastrin
IGF1R insulin-like growth factor 1 receptor
IL6 interleukin 6
MEN1 multiple endocrine neoplasia I
MET MET proto-oncogene, receptor tyrosine kinase
PIEZO2 piezo-type mechanosensitive ion channel component 2
PPY pancreatic polypeptide
SCT secretin
SCTR secretin receptor
SST somatostatin
TNF tumor necrosis factor