abamectin-6081 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the abamectin-6081 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ADD2 adducin 2 (beta)
AIM2 absent in melanoma 2
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCL6 B-cell CLL/lymphoma 6
BEGAIN brain-enriched guanylate kinase-associated
C2ORF72 chromosome 2 open reading frame 72
C3 complement component 3
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CADM4 cell adhesion molecule 4
CASP4 caspase 4, apoptosis-related cysteine peptidase
CD1A CD1a molecule
CDC14B cell division cycle 14B
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COL6A1 collagen, type VI, alpha 1
CRISP1 cysteine-rich secretory protein 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DGCR8 DGCR8 microprocessor complex subunit
DLK1 delta-like 1 homolog (Drosophila)
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
ELAC1 elaC ribonuclease Z 1
EMID1 EMI domain containing 1
EPHB2 EPH receptor B2
ESM1 endothelial cell-specific molecule 1
FAM13C family with sequence similarity 13, member C
FBLN1 fibulin 1
FOXF2 forkhead box F2
FRMD1 FERM domain containing 1
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GLB1L galactosidase, beta 1-like
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR143 G protein-coupled receptor 143
GSTTP1 glutathione S-transferase theta pseudogene 1
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HIC2 hypermethylated in cancer 2
HPX hemopexin
HR hair growth associated
ICA1 islet cell autoantigen 1, 69kDa
IGFBP3 insulin-like growth factor binding protein 3
INHBE inhibin, beta E
IQCK IQ motif containing K
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KIF21B kinesin family member 21B
KLF3 Kruppel-like factor 3 (basic)
KLHL29 kelch-like family member 29
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LPAR4 lysophosphatidic acid receptor 4
LRRC23 leucine rich repeat containing 23
LRRN2 leucine rich repeat neuronal 2
LTC4S leukotriene C4 synthase
LZTS1 leucine zipper, putative tumor suppressor 1
MEOX2 mesenchyme homeobox 2
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MRPL41 mitochondrial ribosomal protein L41
NCR3 natural cytotoxicity triggering receptor 3
NKX2-5 NK2 homeobox 5
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRP2 neuropilin 2
NSUN6 NOP2/Sun domain family, member 6
NUPR1 nuclear protein, transcriptional regulator, 1
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PIPOX pipecolic acid oxidase
PML promyelocytic leukemia
PTPRJ protein tyrosine phosphatase, receptor type, J
PURG purine-rich element binding protein G
R3HDM1 R3H domain containing 1
RGS6 regulator of G-protein signaling 6
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RPS28 ribosomal protein S28
S100A8 S100 calcium binding protein A8
SAMD9 sterile alpha motif domain containing 9
SATB2 SATB homeobox 2
SCN11A sodium channel, voltage gated, type XI alpha subunit
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SLC19A3 solute carrier family 19 (thiamine transporter), member 3
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPRY4 sprouty homolog 4 (Drosophila)
SQSTM1 sequestosome 1
STS steroid sulfatase (microsomal), isozyme S
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TLR2 toll-like receptor 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRIL TLR4 interactor with leucine-rich repeats
TRIM31 tripartite motif containing 31
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TXNIP thioredoxin interacting protein
ULBP1 UL16 binding protein 1
VLDLR very low density lipoprotein receptor
WDR33 WD repeat domain 33

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACSL4 acyl-CoA synthetase long-chain family member 4
ADGRE5 adhesion G protein-coupled receptor E5
AFAP1 actin filament associated protein 1
ALS2CL ALS2 C-terminal like
BCAS1 breast carcinoma amplified sequence 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCORL1 BCL6 corepressor-like 1
BFSP1 beaded filament structural protein 1, filensin
BGLAP bone gamma-carboxyglutamate (gla) protein
C5AR2 complement component 5a receptor 2
C5ORF45 chromosome 5 open reading frame 45
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD82 CD82 molecule
CENPO centromere protein O
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CORO7 coronin 7
CPA4 carboxypeptidase A4
CRY2 cryptochrome circadian clock 2
DCP1A decapping mRNA 1A
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EFNA3 ephrin-A3
ELOVL4 ELOVL fatty acid elongase 4
FAM204A family with sequence similarity 204, member A
FOXN2 forkhead box N2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GAREM GRB2 associated, regulator of MAPK1
GATA4 GATA binding protein 4
GMPR guanosine monophosphate reductase
GPR27 G protein-coupled receptor 27
GRAMD1C GRAM domain containing 1C
HOXA4 homeobox A4
HOXC8 homeobox C8
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL12RB1 interleukin 12 receptor, beta 1
IL22 interleukin 22
ING4 inhibitor of growth family, member 4
INO80D INO80 complex subunit D
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KPNA5 karyopherin alpha 5 (importin alpha 6)
LHX2 LIM homeobox 2
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC20 leucine rich repeat containing 20
LRRC8E leucine rich repeat containing 8 family, member E
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK7 mitogen-activated protein kinase 7
MATK megakaryocyte-associated tyrosine kinase
MVP major vault protein
NCALD neurocalcin delta
NDE1 nudE neurodevelopment protein 1
NEUROD4 neuronal differentiation 4
NRGN neurogranin (protein kinase C substrate, RC3)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAIP2B poly(A) binding protein interacting protein 2B
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PER3 period circadian clock 3
PGBD5 piggyBac transposable element derived 5
PMP22 peripheral myelin protein 22
PODXL2 podocalyxin-like 2
POMT2 protein-O-mannosyltransferase 2
RAB30 RAB30, member RAS oncogene family
RAB40C RAB40C, member RAS oncogene family
RAPSN receptor-associated protein of the synapse
RBM41 RNA binding motif protein 41
RGS19 regulator of G-protein signaling 19
RGS2 regulator of G-protein signaling 2
SCN1B sodium channel, voltage gated, type I beta subunit
SDC3 syndecan 3
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNX16 sorting nexin 16
SPIDR scaffolding protein involved in DNA repair
STAG3L1 stromal antigen 3-like 1 (pseudogene)
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TLR5 toll-like receptor 5
TMCC2 transmembrane and coiled-coil domain family 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM242 transmembrane protein 242
TMLHE trimethyllysine hydroxylase, epsilon
TRAIP TRAF interacting protein
TRIM5 tripartite motif containing 5
TUBA3C tubulin, alpha 3c
TUBG2 tubulin, gamma 2
VAX2 ventral anterior homeobox 2
WDR4 WD repeat domain 4
WLS wntless Wnt ligand secretion mediator
WNT10B wingless-type MMTV integration site family, member 10B
ZBTB22 zinc finger and BTB domain containing 22
ZMYM3 zinc finger, MYM-type 3
ZNF446 zinc finger protein 446
ZNF574 zinc finger protein 574
ZNF747 zinc finger protein 747