abamectin Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
Description Mixture of 80% avermectin B1a and 20% avermectin B1b. (Chemical Entities of Biological Interest Ontology, CHEBI_39214)
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Genes

614 genes differentially expressed following the abamectin small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
DCAF4 DDB1 and CUL4 associated factor 4 6.64759
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 6.30083
BRCA1 breast cancer 1, early onset 6.17783
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 5.64419
DHRS2 dehydrogenase/reductase (SDR family) member 2 5.54162
OPN3 opsin 3 5.25052
KRT33B keratin 33B, type I 5.22017
PHF11 PHD finger protein 11 5.14143
ANGPT1 angiopoietin 1 5.13358
TTLL1 tubulin tyrosine ligase-like family member 1 5.06446
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 5.05397
PIH1D1 PIH1 domain containing 1 5.00673
DYNLT3 dynein, light chain, Tctex-type 3 4.94832
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 4.93239
EXTL2 exostosin-like glycosyltransferase 2 4.89313
KRT34 keratin 34, type I 4.87893
KLHL28 kelch-like family member 28 4.86265
HEXA hexosaminidase A (alpha polypeptide) 4.82469
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 4.81851
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 4.76148
TRH thyrotropin-releasing hormone 4.75925
EVI5 ecotropic viral integration site 5 4.71984
GSR glutathione reductase 4.71738
ATP5MC1 ATP synthase membrane subunit c locus 1 4.71263
GALC galactosylceramidase 4.64511
TPI1 triosephosphate isomerase 1 4.61714
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 4.5869
PAX8 paired box 8 4.58099
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 4.56852
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 4.49798
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 4.49242
RPS4Y1 ribosomal protein S4, Y-linked 1 4.43505
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 4.43258
ZNF669 zinc finger protein 669 4.41178
TPP2 tripeptidyl peptidase II 4.40631
INSL5 insulin-like 5 4.39964
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 4.32812
TTC23 tetratricopeptide repeat domain 23 4.31091
UXS1 UDP-glucuronate decarboxylase 1 4.30554
NEUROD1 neuronal differentiation 1 4.29812
FAHD2A fumarylacetoacetate hydrolase domain containing 2A 4.28721
TMEM147 transmembrane protein 147 4.27955
ABHD14A abhydrolase domain containing 14A 4.27297
EMID1 EMI domain containing 1 4.2713
PTPN6 protein tyrosine phosphatase, non-receptor type 6 4.2707
CD79B CD79b molecule, immunoglobulin-associated beta 4.2684
MDH1 malate dehydrogenase 1, NAD (soluble) 4.24821
HOXC6 homeobox C6 4.233
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 4.19717
PTGES prostaglandin E synthase 4.17768
UNC5C unc-5 homolog C (C. elegans) 4.17629
ECE2 endothelin converting enzyme 2 4.16128
GLI2 GLI family zinc finger 2 4.13528
CEP41 centrosomal protein 41kDa 4.13283
SNX11 sorting nexin 11 4.12682
ZNF345 zinc finger protein 345 4.12197
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 4.09592
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) 4.0917
ZC2HC1C zinc finger, C2HC-type containing 1C 4.09086
ARL4D ADP-ribosylation factor-like 4D 4.08565
MINDY1 MINDY lysine 48 deubiquitinase 1 4.08148
IL33R interleukin 33 receptor 4.06195
ELP1 elongator acetyltransferase complex subunit 1 4.0598
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2 4.05878
TEAD3 TEA domain family member 3 4.05326
ANAPC13 anaphase promoting complex subunit 13 4.03015
SCAF4 SR-related CTD-associated factor 4 4.02002
CA12 carbonic anhydrase XII 4.00577
LRRC32 leucine rich repeat containing 32 3.98046
LSM12 LSM12 homolog (S. cerevisiae) 3.95156
KPNA1 karyopherin alpha 1 (importin alpha 5) 3.94342
CUL5 cullin 5 3.91066
CDH16 cadherin 16, KSP-cadherin 3.90825
CYBB cytochrome b-245, beta polypeptide 3.90772
MBNL3 muscleblind-like splicing regulator 3 3.88567
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 3.87967
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 3.8605
NARS1 asparaginyl-tRNA synthetase 1 3.85697
GTF3A general transcription factor IIIA 3.83866
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) 3.83292
CCDC198 coiled-coil domain containing 198 3.81612
UBA5 ubiquitin-like modifier activating enzyme 5 3.81187
HOXC8 homeobox C8 3.81015
SNX5 sorting nexin 5 3.80504
PLSCR1 phospholipid scramblase 1 3.79934
OR1D2 olfactory receptor, family 1, subfamily D, member 2 3.79846
SIGLEC15 sialic acid binding Ig-like lectin 15 3.78992
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 3.78934
PAPPA2 pappalysin 2 3.77885
EFHD1 EF-hand domain family, member D1 3.77214
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 3.76556
RBBP4 retinoblastoma binding protein 4 3.75916
DUSP22 dual specificity phosphatase 22 3.75044
KYAT1 kynurenine aminotransferase 1 3.74301
HEATR1 HEAT repeat containing 1 3.74194
DEPP1 DEPP autophagy regulator 1 3.73729
FCF1 FCF1 rRNA-processing protein 3.73269
GLUD2 glutamate dehydrogenase 2 3.71608
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 3.71486
PGRMC2 progesterone receptor membrane component 2 3.70456
MED4 mediator complex subunit 4 3.70362
KLHL3 kelch-like family member 3 3.69016
RIOX2 ribosomal oxygenase 2 3.68579
CORO2B coronin, actin binding protein, 2B 3.6828
SLC46A3 solute carrier family 46, member 3 3.67257
FGG fibrinogen gamma chain 3.66158
SNORA21 small nucleolar RNA, H/ACA box 21 3.62404
TERT telomerase reverse transcriptase 3.61557
DRG2 developmentally regulated GTP binding protein 2 3.60357
MAP3K19 mitogen-activated protein kinase kinase kinase 19 3.60278
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 3.60136
GLUD1 glutamate dehydrogenase 1 3.59265
CEP70 centrosomal protein 70kDa 3.5919
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 3.58892
CALCOCO2 calcium binding and coiled-coil domain 2 3.58679
C1RL complement component 1, r subcomponent-like 3.58639
UXT ubiquitously-expressed, prefoldin-like chaperone 3.58121
ZNF185 zinc finger protein 185 (LIM domain) 3.57302
HOXC10 homeobox C10 3.57297
NEK9 NIMA-related kinase 9 3.54744
GPX3 glutathione peroxidase 3 3.54139
RUFY3 RUN and FYVE domain containing 3 3.54005
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 3.52654
CCR8 chemokine (C-C motif) receptor 8 3.52011
ZNF562 zinc finger protein 562 3.51874
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 3.50799
GSTT1 glutathione S-transferase theta 1 3.50492
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 3.48288
C14ORF93 chromosome 14 open reading frame 93 3.47947
HLA-DMA major histocompatibility complex, class II, DM alpha 3.47395
ERG28 ergosterol biosynthesis 28 homolog 3.47258
MTF2 metal response element binding transcription factor 2 3.46597
SLPI secretory leukocyte peptidase inhibitor 3.45498
CHPT1 choline phosphotransferase 1 3.4449
ERICH1 glutamate-rich 1 3.4414
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit 3.43809
SHOX short stature homeobox 3.42896
OGG1 8-oxoguanine DNA glycosylase 3.42846
HLA-G major histocompatibility complex, class I, G 3.42826
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 3.42721
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 3.42609
RAB27A RAB27A, member RAS oncogene family 3.42508
NGRN neugrin, neurite outgrowth associated 3.42463
MRPS31 mitochondrial ribosomal protein S31 3.42366
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) 3.42263
F3 coagulation factor III (thromboplastin, tissue factor) 3.41281
CETP cholesteryl ester transfer protein, plasma 3.41051
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 3.40963
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 3.40339
RSAD1 radical S-adenosyl methionine domain containing 1 3.39796
VPREB1 pre-B lymphocyte 1 3.37812
TIAM1 T-cell lymphoma invasion and metastasis 1 3.37738
HOXC5 homeobox C5 3.36931
BAHCC1 BAH domain and coiled-coil containing 1 3.36822
MYT1L myelin transcription factor 1-like 3.36266
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 3.36266
CD177 CD177 molecule 3.36086
RBX1 ring-box 1, E3 ubiquitin protein ligase 3.35911
SLC6A16 solute carrier family 6, member 16 3.3536
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 3.35141
NUP43 nucleoporin 43kDa 3.35111
DHRS3 dehydrogenase/reductase (SDR family) member 3 3.34557
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 3.34238
TMCO3 transmembrane and coiled-coil domains 3 3.34055
TP53I11 tumor protein p53 inducible protein 11 3.3394
TRAF3IP3 TRAF3 interacting protein 3 3.33847
GCDH glutaryl-CoA dehydrogenase 3.33056
PSORS1C2 psoriasis susceptibility 1 candidate 2 3.32952
NRTN neurturin 3.32582
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 3.32124
DNAL4 dynein, axonemal, light chain 4 3.31512
BTBD18 BTB (POZ) domain containing 18 3.31304
VLDLR very low density lipoprotein receptor 3.30983
CC2D2B coiled-coil and C2 domain containing 2B 3.30775
CCR3 chemokine (C-C motif) receptor 3 3.29733
FOXO1 forkhead box O1 3.28999
SYT13 synaptotagmin XIII 3.28739
S1PR2 sphingosine-1-phosphate receptor 2 3.28697
EPS15 epidermal growth factor receptor pathway substrate 15 3.28529
ZDHHC24 zinc finger, DHHC-type containing 24 3.28341
GRIA4 glutamate receptor, ionotropic, AMPA 4 3.28246
SLC26A4 solute carrier family 26 (anion exchanger), member 4 3.27936
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 3.27754
EXOSC7 exosome component 7 3.2738
PCOLCE2 procollagen C-endopeptidase enhancer 2 3.26708
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 3.26613
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 3.26325
RAB31 RAB31, member RAS oncogene family 3.25445
PDGFRB platelet-derived growth factor receptor, beta polypeptide 3.25229
PCDHGC3 protocadherin gamma subfamily C, 3 3.24408
HACD3 3-hydroxyacyl-CoA dehydratase 3 3.23851
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 3.23826
HDDC2 HD domain containing 2 3.23724
DLG2 discs, large homolog 2 (Drosophila) 3.23525
SNU13 small nuclear ribonucleoprotein 13 3.22579
GGT5 gamma-glutamyltransferase 5 3.2238
OR1G1 olfactory receptor, family 1, subfamily G, member 1 3.2202
DPYD dihydropyrimidine dehydrogenase 3.21671
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 3.21667
MIEF1 mitochondrial elongation factor 1 3.2152
DSCC1 DNA replication and sister chromatid cohesion 1 3.21077
CCDC69 coiled-coil domain containing 69 3.20362
UBE2M ubiquitin-conjugating enzyme E2M 3.20112
IGFBP7 insulin-like growth factor binding protein 7 3.20042
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein 3.2001
UTS2 urotensin 2 3.20002
GJA1 gap junction protein, alpha 1, 43kDa 3.19998
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 3.19478
ODAD2 outer dynein arm docking complex subunit 2 3.19373
FAM162A family with sequence similarity 162, member A 3.19269
BBOF1 basal body orientation factor 1 3.19266
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 3.18972
SNX29 sorting nexin 29 3.18622
SIGLEC5 sialic acid binding Ig-like lectin 5 3.18191
AANAT aralkylamine N-acetyltransferase 3.17691
DNAAF2 dynein, axonemal, assembly factor 2 3.17664
ICAM3 intercellular adhesion molecule 3 3.17649
TG thyroglobulin 3.17361
POLR1D polymerase (RNA) I polypeptide D, 16kDa 3.17194
IFI44L interferon-induced protein 44-like 3.17125
KRT33A keratin 33A, type I 3.16825
MAGEC2 melanoma antigen family C2 3.16806
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 3.16769
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 3.16663
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 3.16554
CP ceruloplasmin (ferroxidase) 3.16219
CYC1 cytochrome c-1 3.16134
VPREB3 pre-B lymphocyte 3 3.15654
RASIP1 Ras interacting protein 1 3.15572
MUC16 mucin 16, cell surface associated 3.15125
SPOP speckle-type POZ protein 3.14924
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 3.14867
LRRN2 leucine rich repeat neuronal 2 3.14405
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 3.13758
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 3.13564
RPS15 ribosomal protein S15 3.13449
RRAGD Ras-related GTP binding D 3.13369
ITGA1 integrin, alpha 1 3.13206
CNPY3 canopy FGF signaling regulator 3 3.12965
WNT7A wingless-type MMTV integration site family, member 7A 3.1264
SALL1 spalt-like transcription factor 1 3.12631
ZNF573 zinc finger protein 573 3.12444
TSHR thyroid stimulating hormone receptor 3.11474
PLA2G12A phospholipase A2, group XIIA 3.11362
GNG5 guanine nucleotide binding protein (G protein), gamma 5 3.1064
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 3.10525
CYCS cytochrome c, somatic 3.09966
BEX4 brain expressed, X-linked 4 3.09461
TSPAN7 tetraspanin 7 3.08956
CSNK1E casein kinase 1, epsilon 3.0891
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 3.08881
IGFBP5 insulin-like growth factor binding protein 5 3.08676
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 3.08181
OSBPL3 oxysterol binding protein-like 3 3.07907
SIRT5 sirtuin 5 3.07736
COPZ2 coatomer protein complex, subunit zeta 2 3.07363
SRY sex determining region Y 3.07234
SRP9 signal recognition particle 9kDa 3.07154
ZNF165 zinc finger protein 165 3.06727
DZIP3 DAZ interacting zinc finger protein 3 3.05803
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene 3.05421
ARL5A ADP-ribosylation factor-like 5A 3.05378
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 3.04971
QPRT quinolinate phosphoribosyltransferase 3.0492
WDR7 WD repeat domain 7 3.04711
MIS18BP1 MIS18 binding protein 1 3.04707
ITM2A integral membrane protein 2A 3.04551
NRCAM neuronal cell adhesion molecule 3.04125
BMP5 bone morphogenetic protein 5 3.03885
ZNF529 zinc finger protein 529 3.03237
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 3.03177
CTSW cathepsin W 3.03036
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 3.02992
DEPTOR DEP domain containing MTOR-interacting protein 3.02843
TRIM5 tripartite motif containing 5 3.02777
AGMAT agmatine ureohydrolase (agmatinase) 3.02643
EDA ectodysplasin A 3.02463
SKAP2 src kinase associated phosphoprotein 2 3.02457
NLGN4Y neuroligin 4, Y-linked 3.02381
KIAA1549L KIAA1549-like 3.02379
TMEM53 transmembrane protein 53 3.01767
COLEC11 collectin sub-family member 11 3.01653
USP24 ubiquitin specific peptidase 24 3.01085
MAGEA12 melanoma antigen family A12 3.00792
IVD isovaleryl-CoA dehydrogenase 3.00751
OR1A2 olfactory receptor, family 1, subfamily A, member 2 3.00239
CTBS chitobiase, di-N-acetyl- 3.00142

decreased expression

Symbol Name Standardized Value
CSK c-src tyrosine kinase -6.42202
LIPF lipase, gastric -6.32556
AFF4 AF4/FMR2 family, member 4 -6.14593
DUSP3 dual specificity phosphatase 3 -5.92737
NPDC1 neural proliferation, differentiation and control, 1 -5.77646
PNLIPRP1 pancreatic lipase-related protein 1 -5.37311
SPAG4 sperm associated antigen 4 -5.3588
CBLIF cobalamin binding intrinsic factor -5.29189
ATP4B ATPase, H+/K+ exchanging, beta polypeptide -5.26595
DACH1 dachshund family transcription factor 1 -5.25776
GPC4 glypican 4 -5.22066
C2CD5 C2 calcium-dependent domain containing 5 -5.09337
MEFV Mediterranean fever -4.88116
DPEP1 dipeptidase 1 (renal) -4.87696
CASP10 caspase 10, apoptosis-related cysteine peptidase -4.85292
GREM1 gremlin 1, DAN family BMP antagonist -4.84746
REG3A regenerating islet-derived 3 alpha -4.81887
CTRL chymotrypsin-like -4.80357
GPSM2 G-protein signaling modulator 2 -4.75913
TEX10 testis expressed 10 -4.74709
NOS3 nitric oxide synthase 3 (endothelial cell) -4.73134
LDB3 LIM domain binding 3 -4.69259
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled -4.69011
TRIM33 tripartite motif containing 33 -4.67495
CELA3A chymotrypsin-like elastase family, member 3A -4.64548
ADRA2A adrenoceptor alpha 2A -4.64546
TUBB6 tubulin, beta 6 class V -4.63305
STX17 syntaxin 17 -4.62286
CPA1 carboxypeptidase A1 (pancreatic) -4.60445
ETNK1 ethanolamine kinase 1 -4.59784
ESRP1 epithelial splicing regulatory protein 1 -4.59085
ESRP2 epithelial splicing regulatory protein 2 -4.5865
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 -4.56117
UTF1 undifferentiated embryonic cell transcription factor 1 -4.50809
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) -4.48962
GPR162 G protein-coupled receptor 162 -4.48603
MFSD6 major facilitator superfamily domain containing 6 -4.47843
CCL24 chemokine (C-C motif) ligand 24 -4.47326
WDR45B WD repeat domain 45B -4.44895
TDRD7 tudor domain containing 7 -4.43559
VANGL1 VANGL planar cell polarity protein 1 -4.43395
RAB5A RAB5A, member RAS oncogene family -4.43287
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 -4.42601
DOP1B DOP1 leucine zipper like protein B -4.40572
MYO5A myosin VA (heavy chain 12, myoxin) -4.40177
KLK12 kallikrein-related peptidase 12 -4.39757
ATAD2B ATPase family, AAA domain containing 2B -4.34102
GP2 glycoprotein 2 (zymogen granule membrane) -4.33972
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -4.32475
CTRC chymotrypsin C (caldecrin) -4.31053
B9D2 B9 protein domain 2 -4.30416
ZNF528 zinc finger protein 528 -4.28759
ICA1 islet cell autoantigen 1, 69kDa -4.28753
CLPS colipase, pancreatic -4.28111
CPA2 carboxypeptidase A2 (pancreatic) -4.26541
PDIA2 protein disulfide isomerase family A, member 2 -4.26427
CLEC5A C-type lectin domain family 5, member A -4.24165
MANSC1 MANSC domain containing 1 -4.24088
MUC6 mucin 6, oligomeric mucus/gel-forming -4.23763
PAN2 PAN2 poly(A) specific ribonuclease subunit -4.23407
RPRM reprimo, TP53 dependent G2 arrest mediator candidate -4.22503
EDAR ectodysplasin A receptor -4.21934
DMRT1 doublesex and mab-3 related transcription factor 1 -4.1905
GIP gastric inhibitory polypeptide -4.17522
DCX doublecortin -4.16181
LCMT2 leucine carboxyl methyltransferase 2 -4.15964
PHEX phosphate regulating endopeptidase homolog, X-linked -4.14462
CERS6 ceramide synthase 6 -4.14174
PPCDC phosphopantothenoylcysteine decarboxylase -4.13521
SOX2 SRY (sex determining region Y)-box 2 -4.11821
STK38L serine/threonine kinase 38 like -4.10953
LRTM1 leucine-rich repeats and transmembrane domains 1 -4.09964
RFX5 regulatory factor X, 5 (influences HLA class II expression) -4.09303
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 -4.09275
BCL2L14 BCL2-like 14 (apoptosis facilitator) -4.08658
CELP carboxyl ester lipase pseudogene -4.08217
CPNE1 copine I -4.07934
MBTPS2 membrane-bound transcription factor peptidase, site 2 -4.07871
EPN3 epsin 3 -4.06736
MNX1 motor neuron and pancreas homeobox 1 -4.06399
TRIM48 tripartite motif containing 48 -4.05563
AGFG2 ArfGAP with FG repeats 2 -4.05368
PNLIP pancreatic lipase -4.04697
CELA2A chymotrypsin-like elastase family, member 2A -4.03152
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -4.02719
GPBP1L1 GC-rich promoter binding protein 1-like 1 -4.02663
BDH1 3-hydroxybutyrate dehydrogenase, type 1 -4.01565
NADSYN1 NAD synthetase 1 -4.00203
NOL4 nucleolar protein 4 -3.99993
SH3BP5 SH3-domain binding protein 5 (BTK-associated) -3.99822
ZNF710 zinc finger protein 710 -3.99573
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 -3.99321
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -3.98141
FOLH1B folate hydrolase 1B -3.96058
MYOM2 myomesin 2 -3.9586
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -3.94858
CD300C CD300c molecule -3.94429
TRIM15 tripartite motif containing 15 -3.94072
PAIP2B poly(A) binding protein interacting protein 2B -3.93342
NACAD NAC alpha domain containing -3.92877
NFE2L3 nuclear factor, erythroid 2-like 3 -3.91087
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) -3.90526
STARD5 StAR-related lipid transfer (START) domain containing 5 -3.90363
TBC1D12 TBC1 domain family, member 12 -3.89984
H2AJ H2A.J histone -3.89064
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -3.87467
AOC4P amine oxidase, copper containing 4, pseudogene -3.87264
OR7C1 olfactory receptor, family 7, subfamily C, member 1 -3.86697
REEP2 receptor accessory protein 2 -3.8606
LHX6 LIM homeobox 6 -3.8542
PDK1 pyruvate dehydrogenase kinase, isozyme 1 -3.83883
PYGM phosphorylase, glycogen, muscle -3.81704
TRAF5 TNF receptor-associated factor 5 -3.79537
MYCT1 myc target 1 -3.79129
PAX9 paired box 9 -3.78632
CELA3B chymotrypsin-like elastase family, member 3B -3.77063
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -3.76394
TXNL4B thioredoxin-like 4B -3.7581
IL5RA interleukin 5 receptor, alpha -3.75194
SKIL SKI-like proto-oncogene -3.74707
RESF1 retroelement silencing factor 1 -3.73841
SGSH N-sulfoglucosamine sulfohydrolase -3.73606
FAM163A family with sequence similarity 163, member A -3.73419
BCAS3 breast carcinoma amplified sequence 3 -3.73267
VAV1 vav 1 guanine nucleotide exchange factor -3.7264
RNF41 ring finger protein 41, E3 ubiquitin protein ligase -3.71697
TRIM14 tripartite motif containing 14 -3.71382
PLCL2 phospholipase C-like 2 -3.71226
PLK1 polo-like kinase 1 -3.69798
LYZL6 lysozyme-like 6 -3.69383
BPHL biphenyl hydrolase-like (serine hydrolase) -3.68987
SPDEF SAM pointed domain containing ETS transcription factor -3.68947
CTRB2 chymotrypsinogen B2 -3.67783
CREB1 cAMP responsive element binding protein 1 -3.67691
LMTK1 lemur tail kinase 1 -3.66379
CGREF1 cell growth regulator with EF-hand domain 1 -3.63976
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -3.63139
RBKS ribokinase -3.62411
NR4A3 nuclear receptor subfamily 4, group A, member 3 -3.61083
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -3.60785
ERGIC3 ERGIC and golgi 3 -3.60775
FBP1 fructose-1,6-bisphosphatase 1 -3.60723
IFT81 intraflagellar transport 81 -3.60616
GCC2 GRIP and coiled-coil domain containing 2 -3.59424
DSE dermatan sulfate epimerase -3.59157
PRSS1 protease, serine, 1 (trypsin 1) -3.58995
PSD pleckstrin and Sec7 domain containing -3.58841
CYFIP1 cytoplasmic FMR1 interacting protein 1 -3.58473
GPR183 G protein-coupled receptor 183 -3.58371
KLK3 kallikrein-related peptidase 3 -3.57902
CIAO3 cytosolic iron-sulfur assembly component 3 -3.57867
TSPAN15 tetraspanin 15 -3.57333
MCL1 myeloid cell leukemia 1 -3.57178
TRPM1 transient receptor potential cation channel, subfamily M, member 1 -3.55899
NCF2 neutrophil cytosolic factor 2 -3.55857
PDE3A phosphodiesterase 3A, cGMP-inhibited -3.55532
NRBP1 nuclear receptor binding protein 1 -3.55076
CELA2B chymotrypsin-like elastase family, member 2B -3.544
ZNF263 zinc finger protein 263 -3.54217
KLK2 kallikrein-related peptidase 2 -3.54197
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) -3.52986
CORO1C coronin, actin binding protein, 1C -3.52546
ZNF3 zinc finger protein 3 -3.5249
NCK2 NCK adaptor protein 2 -3.52405
MED21 mediator complex subunit 21 -3.51643
GRIA3 glutamate receptor, ionotropic, AMPA 3 -3.51623
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.5162
PTPRO protein tyrosine phosphatase, receptor type, O -3.51117
USP15 ubiquitin specific peptidase 15 -3.5077
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 -3.50613
DPH2 DPH2 homolog (S. cerevisiae) -3.50313
RYBP RING1 and YY1 binding protein -3.4978
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 -3.49736
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -3.49724
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -3.49518
ZC3H7A zinc finger CCCH-type containing 7A -3.49076
SHB Src homology 2 domain containing adaptor protein B -3.49058
GOLGA4 golgin A4 -3.48547
BLTP3B bridge-like lipid transfer protein family member 3B -3.48413
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -3.47507
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -3.47156
AREG amphiregulin -3.47122
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 -3.46995
RAF1 Raf-1 proto-oncogene, serine/threonine kinase -3.46659
ZBTB39 zinc finger and BTB domain containing 39 -3.46375
FILIP1L filamin A interacting protein 1-like -3.4623
CHRDL1 chordin-like 1 -3.45998
BBS10 Bardet-Biedl syndrome 10 -3.4481
ZNF816 zinc finger protein 816 -3.44483
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -3.44417
PI4KB phosphatidylinositol 4-kinase, catalytic, beta -3.44229
LINC00115 long intergenic non-protein coding RNA 115 -3.441
KANSL3 KAT8 regulatory NSL complex subunit 3 -3.44068
DEF8 differentially expressed in FDCP 8 homolog (mouse) -3.43437
ZNF835 zinc finger protein 835 -3.43372
GADD45G growth arrest and DNA-damage-inducible, gamma -3.43198
CPD carboxypeptidase D -3.43034
AMBRA1 autophagy/beclin-1 regulator 1 -3.42711
PITPNA phosphatidylinositol transfer protein, alpha -3.42452
TPD52 tumor protein D52 -3.41987
OR7C2 olfactory receptor, family 7, subfamily C, member 2 -3.4151
TTC13 tetratricopeptide repeat domain 13 -3.41248
DCTN5 dynactin 5 (p25) -3.40887
ECPAS Ecm29 proteasome adaptor and scaffold -3.39698
DNM3 dynamin 3 -3.39471
FBXO28 F-box protein 28 -3.39339
CEP72 centrosomal protein 72kDa -3.38923
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -3.38291
H2AC25 H2A clustered histone 25 -3.37451
KLHL41 kelch-like family member 41 -3.37113
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -3.37051
GON4L gon-4-like (C. elegans) -3.36939
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) -3.36832
TNNC2 troponin C type 2 (fast) -3.36807
ASPHD1 aspartate beta-hydroxylase domain containing 1 -3.35659
OPHN1 oligophrenin 1 -3.35464
CAB39 calcium binding protein 39 -3.35044
UIMC1 ubiquitin interaction motif containing 1 -3.34779
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 -3.34715
HDAC4 histone deacetylase 4 -3.3424
TCTN2 tectonic family member 2 -3.33906
MUS81 MUS81 structure-specific endonuclease subunit -3.33815
FZD3 frizzled class receptor 3 -3.33698
TOR4A torsin family 4, member A -3.32514
DNAI7 dynein axonemal intermediate chain 7 -3.32491
SPON2 spondin 2, extracellular matrix protein -3.32478
POU4F2 POU class 4 homeobox 2 -3.32254
HNF1A HNF1 homeobox A -3.31609
MAML1 mastermind-like 1 (Drosophila) -3.31386
SLC26A6 solute carrier family 26 (anion exchanger), member 6 -3.30962
EREG epiregulin -3.30668
IL18R1 interleukin 18 receptor 1 -3.30583
YAF2 YY1 associated factor 2 -3.30057
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 -3.28995
AMPD1 adenosine monophosphate deaminase 1 -3.28986
OGFR opioid growth factor receptor -3.28733
CCT2 chaperonin containing TCP1, subunit 2 (beta) -3.27659
IL15RA interleukin 15 receptor, alpha -3.27421
DKK2 dickkopf WNT signaling pathway inhibitor 2 -3.26882
LUC7L LUC7-like (S. cerevisiae) -3.26527
MERTK MER proto-oncogene, tyrosine kinase -3.24857
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -3.23889
PENK proenkephalin -3.23793
LDLRAP1 low density lipoprotein receptor adaptor protein 1 -3.23102
GFOD2 glucose-fructose oxidoreductase domain containing 2 -3.22898
FAAH fatty acid amide hydrolase -3.22808
FAM107A family with sequence similarity 107, member A -3.22448
EMC1 ER membrane protein complex subunit 1 -3.22423
LRP12 low density lipoprotein receptor-related protein 12 -3.22193
CSNK1D casein kinase 1, delta -3.22113
SPATS2L spermatogenesis associated, serine-rich 2-like -3.22095
TCF12 transcription factor 12 -3.21784
PCDH7 protocadherin 7 -3.21595
PEX1 peroxisomal biogenesis factor 1 -3.21561
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -3.21187
FRK fyn-related Src family tyrosine kinase -3.21087
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 -3.20643
REG1A regenerating islet-derived 1 alpha -3.20556
FAM124B family with sequence similarity 124B -3.2004
FBXO46 F-box protein 46 -3.19569
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 -3.19046
TUT7 terminal uridylyl transferase 7 -3.18931
ZDHHC17 zinc finger, DHHC-type containing 17 -3.1891
CDC42SE1 CDC42 small effector 1 -3.18632
TRIM17 tripartite motif containing 17 -3.18371
KLF8 Kruppel-like factor 8 -3.1815
SYT5 synaptotagmin V -3.18005
SCN8A sodium channel, voltage gated, type VIII alpha subunit -3.17671
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 -3.17627
FAM32A family with sequence similarity 32, member A -3.17092
UBAP1 ubiquitin associated protein 1 -3.1668
CHERP calcium homeostasis endoplasmic reticulum protein -3.16502
STIP1 stress-induced phosphoprotein 1 -3.158
GALR2 galanin receptor 2 -3.15008
ZNF235 zinc finger protein 235 -3.13865
MYH6 myosin, heavy chain 6, cardiac muscle, alpha -3.13659
ATF6 activating transcription factor 6 -3.13466
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A -3.13275
ENOSF1 enolase superfamily member 1 -3.13134
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 -3.12944
PAGE4 P antigen family, member 4 (prostate associated) -3.12501
INTS13 integrator complex subunit 13 -3.1238
PPARD peroxisome proliferator-activated receptor delta -3.11789
GIN1 gypsy retrotransposon integrase 1 -3.11627
PGAP1 post-GPI attachment to proteins 1 -3.10789
MOBP myelin-associated oligodendrocyte basic protein -3.10708
TDRKH tudor and KH domain containing -3.10664
TJAP1 tight junction associated protein 1 (peripheral) -3.10382
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -3.10347
TUBB3 tubulin, beta 3 class III -3.09444
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 -3.09425
EXOSC10 exosome component 10 -3.08747
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -3.08636
ZBTB40 zinc finger and BTB domain containing 40 -3.08418
NVL nuclear VCP-like -3.07618
BAIAP3 BAI1-associated protein 3 -3.07595
PCCA propionyl CoA carboxylase, alpha polypeptide -3.07389
ZNF215 zinc finger protein 215 -3.07262
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A -3.0723
GFOD1 glucose-fructose oxidoreductase domain containing 1 -3.07021
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 -3.06966
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) -3.06681
WBP11 WW domain binding protein 11 -3.06628
COG4 component of oligomeric golgi complex 4 -3.06271
FBN1 fibrillin 1 -3.06038
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 -3.05639
KLHL18 kelch-like family member 18 -3.05411
TINAGL1 tubulointerstitial nephritis antigen-like 1 -3.05167
ZC3H11A zinc finger CCCH-type containing 11A -3.04525
BCAT1 branched chain amino-acid transaminase 1, cytosolic -3.04276
TSPYL5 TSPY-like 5 -3.03544
AUP1 ancient ubiquitous protein 1 -3.03349
TBRG4 transforming growth factor beta regulator 4 -3.03271
ANKZF1 ankyrin repeat and zinc finger domain containing 1 -3.02999
ISL1 ISL LIM homeobox 1 -3.02957
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -3.02428
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -3.02242
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 -3.01821
CXCR3 chemokine (C-X-C motif) receptor 3 -3.01527
WDR82 WD repeat domain 82 -3.01499
COLGALT2 collagen beta(1-O)galactosyltransferase 2 -3.01269
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase -3.00817
MCM9 minichromosome maintenance complex component 9 -3.00794
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) -3.00762
NKX2-5 NK2 homeobox 5 -3.00714
TNR tenascin R -3.00701
SIRPA signal-regulatory protein alpha -3.00236