| Dataset | GeneRIF Biological Term Annotations |
| Category | structural or functional annotations |
| Type | biological term |
| Description | ABL proto-oncogene 2, non-receptor tyrosine kinase|This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009] (NCBI Entrez Gene Database, 27) |
| Similar Terms | |
| Downloads & Tools |
2 genes co-occuring with the biological term abl2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
