any anomaly in the number of the CD4-positive, CD25-positive T cell subset which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release (Mammalian Phenotype Ontology, MP_0012773)
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1 gene mutations causing the abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.