abnormal axon extension Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description abnormality in the ability of an axon to exhibit long distance growth of a single axon process from a neuron cell body involved in cellular development (Mammalian Phenotype Ontology, MP_0003651)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003651
Similar Terms
Downloads & Tools


51 gene mutations causing the abnormal axon extension phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BASP1 brain abundant, membrane attached signal protein 1
BAX BCL2-associated X protein
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CFL1 cofilin 1 (non-muscle)
CHN1 chimerin 1
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
CNTF ciliary neurotrophic factor
DLX5 distal-less homeobox 5
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPHB2 EPH receptor B2
FEZF1 FEZ family zinc finger 1
GAP43 growth associated protein 43
GPHN gephyrin
GPM6A glycoprotein M6A
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
KIF26A kinesin family member 26A
KIF2A kinesin heavy chain member 2A
KLF7 Kruppel-like factor 7 (ubiquitous)
L1CAM L1 cell adhesion molecule
LEPR leptin receptor
LRRK2 leucine-rich repeat kinase 2
MAP1B microtubule-associated protein 1B
MAPT microtubule-associated protein tau
MEGF8 multiple EGF-like-domains 8
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2
MET MET proto-oncogene, receptor tyrosine kinase
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MUSK muscle, skeletal, receptor tyrosine kinase
NEFH neurofilament, heavy polypeptide
NFIA nuclear factor I/A
NGEF neuronal guanine nucleotide exchange factor
NGFR nerve growth factor receptor
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRN1 neuritin 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OR8A1 olfactory receptor, family 8, subfamily A, member 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PAX2 paired box 2
PROKR2 prokineticin receptor 2
PTPRS protein tyrosine phosphatase, receptor type, S
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RTN4 reticulon 4
RTN4R reticulon 4 receptor
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SH2D3C SH2 domain containing 3C
SYN3 synapsin III
UNC5D unc-5 homolog D (C. elegans)
VAMP7 vesicle-associated membrane protein 7
ZBTB18 zinc finger and BTB domain containing 18