abnormal circulating glucocorticoid level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description aberrant blood concentration of the corticosteroids regulating carbohydrate metabolism and exhibiting anti-inflammatory activity (Mammalian Phenotype Ontology, MP_0003366)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003366
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Genes

71 gene mutations causing the abnormal circulating glucocorticoid level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACD adrenocortical dysplasia homolog (mouse)
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
AGTR2 angiotensin II receptor, type 2
APOE apolipoprotein E
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
AVPR1A arginine vasopressin receptor 1A
AVPR1B arginine vasopressin receptor 1B
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CLOCK clock circadian regulator
CNR1 cannabinoid receptor 1 (brain)
CRH corticotropin releasing hormone
CRHR1 corticotropin releasing hormone receptor 1
CRTC2 CREB regulated transcription coactivator 2
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DFNB31 deafness, autosomal recessive 31
DHCR7 7-dehydrocholesterol reductase
DLG4 discs, large homolog 4 (Drosophila)
DRD2 dopamine receptor D2
FKBP5 FK506 binding protein 5
GAL galanin/GMAP prepropeptide
GHR growth hormone receptor
GRID2 glutamate receptor, ionotropic, delta 2
GTF2IRD1 GTF2I repeat domain containing 1
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HMGN1 high mobility group nucleosome binding domain 1
HMGN3 high mobility group nucleosomal binding domain 3
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
IFITM1 interferon induced transmembrane protein 1
IL1B interleukin 1, beta
LDLR low density lipoprotein receptor
LEP leptin
LEPR leptin receptor
LIPC lipase, hepatic
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MCHR1 melanin-concentrating hormone receptor 1
MEN1 multiple endocrine neoplasia I
NMU neuromedin U
NPY1R neuropeptide Y receptor Y1
NPY2R neuropeptide Y receptor Y2
NPY5R neuropeptide Y receptor Y5
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PDYN prodynorphin
PITPNA phosphatidylinositol transfer protein, alpha
PLA2G10 phospholipase A2, group X
PLAT plasminogen activator, tissue
POMC proopiomelanocortin
PRLHR prolactin releasing hormone receptor
PROP1 PROP paired-like homeobox 1
RAI1 retinoic acid induced 1
SCG5 secretogranin V
SELM selenoprotein M
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SST somatostatin
STAR steroidogenic acute regulatory protein
TACR1 tachykinin receptor 1
TBX19 T-box 19
TGFB1 transforming growth factor, beta 1
TLR2 toll-like receptor 2
TRAF3 TNF receptor-associated factor 3
UCN urocortin
UCN2 urocortin 2
VGF VGF nerve growth factor inducible
WFS1 Wolfram syndrome 1 (wolframin)
ZEB1 zinc finger E-box binding homeobox 1