abnormal circulating interferon-beta level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the amount in the blood of one of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA with antiviral, antiproliferative, and immunomodulating activity (Mammalian Phenotype Ontology, MP_0008550)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008550
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Genes

10 gene mutations causing the abnormal circulating interferon-beta level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADAR adenosine deaminase, RNA-specific
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
GPR183 G protein-coupled receptor 183
IFNB1 interferon, beta 1, fibroblast
MAVS mitochondrial antiviral signaling protein
MB21D1 Mab-21 domain containing 1
MMP9 matrix metallopeptidase 9
PELI1 pellino E3 ubiquitin protein ligase 1
TMEM173 transmembrane protein 173
USP21 ubiquitin specific peptidase 21
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