abnormal digestive system development Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description abnormal formation of the organ system that converts ingested food to nutrients and energy (Mammalian Phenotype Ontology, MP_0003119)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003119
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62 gene mutations causing the abnormal digestive system development phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
APC adenomatous polyposis coli
BMP4 bone morphogenetic protein 4
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
COL19A1 collagen, type XIX, alpha 1
CRB2 crumbs family member 2
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DACT1 dishevelled-binding antagonist of beta-catenin 1
EFNB2 ephrin-B2
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERCC5 excision repair cross-complementation group 5
FAM20B family with sequence similarity 20, member B
FGF10 fibroblast growth factor 10
FOXA2 forkhead box A2
FOXF1 forkhead box F1
FOXL1 forkhead box L1
FOXP4 forkhead box P4
FURIN furin (paired basic amino acid cleaving enzyme)
GATA4 GATA binding protein 4
GLI2 GLI family zinc finger 2
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IRF6 interferon regulatory factor 6
LDB1 LIM domain binding 1
MAPK7 mitogen-activated protein kinase 7
MCM4 minichromosome maintenance complex component 4
MIXL1 Mix paired-like homeobox
NCKAP1 NCK-associated protein 1
NKX2-1 NK2 homeobox 1
NKX2-3 NK2 homeobox 3
NODAL nodal growth differentiation factor
NOG noggin
NR6A1 nuclear receptor subfamily 6, group A, member 1
OTX2 orthodenticle homeobox 2
OVOL2 ovo-like zinc finger 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PDX1 pancreatic and duodenal homeobox 1
PEX5 peroxisomal biogenesis factor 5
PGAP1 post-GPI attachment to proteins 1
PITX2 paired-like homeodomain 2
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PTK2 protein tyrosine kinase 2
PXN paxillin
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RDH10 retinol dehydrogenase 10 (all-trans)
ROR2 receptor tyrosine kinase-like orphan receptor 2
RSPO2 R-spondin 2
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SALL4 spalt-like transcription factor 4
SHH sonic hedgehog
SLIT2 slit homolog 2 (Drosophila)
SMAD2 SMAD family member 2
SMAD5 SMAD family member 5
SOX17 SRY (sex determining region Y)-box 17
TBX6 T-box 6
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TLR4 toll-like receptor 4
TP63 tumor protein p63
TWSG1 twisted gastrulation BMP signaling modulator 1
VANGL2 VANGL planar cell polarity protein 2
VCL vinculin
WNT3A wingless-type MMTV integration site family, member 3A
WNT5A wingless-type MMTV integration site family, member 5A