abnormal ekg Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0003115
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Genes

145 genes associated with the abnormal ekg phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
SCN10A sodium channel, voltage gated, type X alpha subunit 2.64488
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein 2.04042
SCN5A sodium channel, voltage gated, type V alpha subunit 1.95577
NFIA nuclear factor I/A 1.86605
ARHGAP24 Rho GTPase activating protein 24 1.84227
CEP85L centrosomal protein 85kDa-like 1.75985
TBX5 T-box 5 1.60335
CAV1 caveolin 1, caveolae protein, 22kDa 1.57384
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 1.54733
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.45654
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 1.44286
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.43975
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 1.04918
CNOT1 CCR4-NOT transcription complex, subunit 1 1.04365
STK32B serine/threonine kinase 32B 0.969142
XYLB xylulokinase homolog (H. influenzae) 0.942765
EXOG endo/exonuclease (5'-3'), endonuclease G-like 0.932945
ACVR2B activin A receptor, type IIB 0.928309
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 0.919744
SLIT2 slit homolog 2 (Drosophila) 0.919744
SFRP2 secreted frizzled-related protein 2 0.919744
RYR2 ryanodine receptor 2 (cardiac) 0.916356
CFAP44 cilia and flagella associated protein 44 0.893139
PDE4B phosphodiesterase 4B, cAMP-specific 0.882984
NPAS3 neuronal PAS domain protein 3 0.861012
TBC1D2B TBC1 domain family, member 2B 0.840142
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.831588
ETV6 ets variant 6 0.825497
COL26A1 collagen, type XXVI, alpha 1 0.824663
CD244 CD244 molecule, natural killer cell receptor 2B4 0.821408
TLR2 toll-like receptor 2 0.817516
HSPA8 heat shock 70kDa protein 8 0.812214
TSPYL1 TSPY-like 1 0.807106
CXCL9 chemokine (C-X-C motif) ligand 9 0.802966
KIAA0391 KIAA0391 0.802966
CDKN3 cyclin-dependent kinase inhibitor 3 0.790435
NRG2 neuregulin 2 0.789787
MAPK6 mitogen-activated protein kinase 6 0.778318
GREB1 growth regulation by estrogen in breast cancer 1 0.772842
FBXL17 F-box and leucine-rich repeat protein 17 0.767696
PDE5A phosphodiesterase 5A, cGMP-specific 0.766703
RNF175 ring finger protein 175 0.762459
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.743226
RNF207 ring finger protein 207 0.739714
GRM8 glutamate receptor, metabotropic 8 0.726078
AHCYL2 adenosylhomocysteinase-like 2 0.726078
ADCY8 adenylate cyclase 8 (brain) 0.703894
FAM169A family with sequence similarity 169, member A 0.697013
PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 0.690584
ZNF518A zinc finger protein 518A 0.684556
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 0.684556
ABLIM3 actin binding LIM protein family, member 3 0.666599
BMP3 bone morphogenetic protein 3 0.659244
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.657251
CGREF1 cell growth regulator with EF-hand domain 1 0.654304
LRRC4C leucine rich repeat containing 4C 0.651923
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 0.644641
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.639858
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 0.637546
PTBP2 polypyrimidine tract binding protein 2 0.633071
ANGPT1 angiopoietin 1 0.628781
SYT17 synaptotagmin XVII 0.614969
DENND4A DENN/MADD domain containing 4A 0.605862
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.599122
PXDNL peroxidasin-like 0.592807
UVRAG UV radiation resistance associated 0.573902
TDRD1 tudor domain containing 1 0.522136
LIG3 ligase III, DNA, ATP-dependent 0.451828
MEIS1 Meis homeobox 1 0.442037
NKX2-5 NK2 homeobox 5 0.423616
ITGA9 integrin, alpha 9 0.421597
FADS1 fatty acid desaturase 1 0.406142
WNT11 wingless-type MMTV integration site family, member 11 0.385513
C18ORF21 chromosome 18 open reading frame 21 0.366298
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding) 0.364668
DPT dermatopontin 0.364396
TMEM44 transmembrane protein 44 0.362071
ARHGAP10 Rho GTPase activating protein 10 0.362071
PTPRG protein tyrosine phosphatase, receptor type, G 0.361026
RPRD1A regulation of nuclear pre-mRNA domain containing 1A 0.359767
PDE3A phosphodiesterase 3A, cGMP-inhibited 0.359285
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.359285
CLDN15 claudin 15 0.353554
IL5RA interleukin 5 receptor, alpha 0.353554
ELMO1 engulfment and cell motility 1 0.353554
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.353554
SAMD3 sterile alpha motif domain containing 3 0.353554
TTN titin 0.353554
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.353554
OSBPL6 oxysterol binding protein-like 6 0.350097
MYO3A myosin IIIA 0.347466
CNTNAP2 contactin associated protein-like 2 0.347466
CCND2 cyclin D2 0.347466
PDZRN3 PDZ domain containing ring finger 3 0.347466
VWC2L von Willebrand factor C domain containing protein 2-like 0.345435
CLDN14 claudin 14 0.345435
BCL6 B-cell CLL/lymphoma 6 0.343784
FOXP1 forkhead box P1 0.343784
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.343784
LDB2 LIM domain binding 2 0.342328
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 0.341006
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 0.341006
PRKCE protein kinase C, epsilon 0.341006
ADAMTSL1 ADAMTS-like 1 0.341006
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 0.341006
FGF14 fibroblast growth factor 14 0.341006
MBP myelin basic protein 0.339843
MFSD2A major facilitator superfamily domain containing 2A 0.339843
CREBBP CREB binding protein 0.339843
NME7 NME/NM23 family member 7 0.338964
NUAK1 NUAK family, SNF1-like kinase, 1 0.338954
UNC13C unc-13 homolog C (C. elegans) 0.338885
FRMD6 FERM domain containing 6 0.338806
NCOA2 nuclear receptor coactivator 2 0.336775
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 0.32686
AJAP1 adherens junctions associated protein 1 0.324554
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 0.32303
KCNK1 potassium channel, two pore domain subfamily K, member 1 0.31925
SOX5 SRY (sex determining region Y)-box 5 0.317491
TUSC3 tumor suppressor candidate 3 0.317283
KLF12 Kruppel-like factor 12 0.311525
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.311525
CORIN corin, serine peptidase 0.311369
C11ORF21 chromosome 11 open reading frame 21 0.306631
USP31 ubiquitin specific peptidase 31 0.306078
TCEA3 transcription elongation factor A (SII), 3 0.30386
LPP LIM domain containing preferred translocation partner in lipoma 0.30304
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5 0.288172
SLC22A23 solute carrier family 22, member 23 0.285115
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 0.28141
ASTN1 astrotactin 1 0.280606
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.278331
AKAP6 A kinase (PRKA) anchor protein 6 0.276638
LYRM4 LYR motif containing 4 0.276412
CCDC141 coiled-coil domain containing 141 0.275741
SLCO3A1 solute carrier organic anion transporter family, member 3A1 0.259433
NUBPL nucleotide binding protein-like 0.259433
NRG3 neuregulin 3 0.259433
CELF4 CUGBP, Elav-like family member 4 0.254693
PALLD palladin, cytoskeletal associated protein 0.254693
NKAIN2 Na+/K+ transporting ATPase interacting 2 0.254693
CERKL ceramide kinase-like 0.254693
THEMIS thymocyte selection associated 0.248712
ADH6 alcohol dehydrogenase 6 (class V) 0.246422
HMCN1 hemicentin 1 0.241372