abnormal folliculo-stellate cell morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the star-shaped and follicle-forming cells in the anterior pituitary gland that stain positive for S-100 protein (a marker for FS-cells); ascribed functions include the formation of an extensive and complex tridimentional network, scavenger activity by engulfing degenerated cells, paracrine regulation of endocrine cells by producing various growth factors and cytokines, such as interleukin-6, leukemia inhibitory factor, basic fibroblastic growth factor, vascular endothelial cell growth factor and follistatin, and large-scale inter-cellular communication by means of their long cytoplasmic processes and gap junctions (Mammalian Phenotype Ontology, MP_0013341)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0013341
Similar Terms
Downloads & Tools


1 gene mutations causing the abnormal folliculo-stellate cell morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ANXA1 annexin A1