abnormal grip strength Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description altered ability to grasp and hold objects, often measured as time spent hanging from an object or wire (Mammalian Phenotype Ontology, MP_0001515)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001515
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180 gene mutations causing the abnormal grip strength phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACHE acetylcholinesterase (Yt blood group)
ACTA1 actin, alpha 1, skeletal muscle
AFF3 AF4/FMR2 family, member 3
AHCYL1 adenosylhomocysteinase-like 1
ANKH ANKH inorganic pyrophosphate transport regulator
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARCN1 archain 1
ARID4A AT rich interactive domain 4A (RBP1-like)
ASCC3 activating signal cointegrator 1 complex subunit 3
B9D1 B9 protein domain 1
BACE1 beta-site APP-cleaving enzyme 1
BBS4 Bardet-Biedl syndrome 4
BBS5 Bardet-Biedl syndrome 5
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CASP12 caspase 12 (gene/pseudogene)
CAV1 caveolin 1, caveolae protein, 22kDa
CBX5 chromobox homolog 5
CD200 CD200 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD86 CD86 molecule
CDH23 cadherin-related 23
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CHD7 chromodomain helicase DNA binding protein 7
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CLDN11 claudin 11
CLK1 CDC-like kinase 1
CNTF ciliary neurotrophic factor
COL12A1 collagen, type XII, alpha 1
COL4A1 collagen, type IV, alpha 1
COMP cartilage oligomeric matrix protein
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung)
CPE carboxypeptidase E
CRYAB crystallin, alpha B
CTF1 cardiotrophin 1
CYB561 cytochrome b561
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DARS2 aspartyl-tRNA synthetase 2, mitochondrial
DCX doublecortin
DLG4 discs, large homolog 4 (Drosophila)
DMD dystrophin
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5
DNASE1L2 deoxyribonuclease I-like 2
DTNA dystrobrevin, alpha
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
ELFN1 extracellular leucine-rich repeat and fibronectin type III domain containing 1
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
ELMO1 engulfment and cell motility 1
ELMOD1 ELMO/CED-12 domain containing 1
EN2 engrailed homeobox 2
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHA4 EPH receptor A4
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EYA3 EYA transcriptional coactivator and phosphatase 3
FABP3 fatty acid binding protein 3, muscle and heart
FAM117B family with sequence similarity 117, member B
FAM83G family with sequence similarity 83, member G
FBN2 fibrillin 2
FBXO11 F-box protein 11
FBXO47 F-box protein 47
FGD4 FYVE, RhoGEF and PH domain containing 4
FGF10 fibroblast growth factor 10
FGF14 fibroblast growth factor 14
FLOT2 flotillin 2
FMR1 fragile X mental retardation 1
FOXB1 forkhead box B1
FOXP2 forkhead box P2
FXR1 fragile X mental retardation, autosomal homolog 1
GAA glucosidase, alpha; acid
GAMT guanidinoacetate N-methyltransferase
GARS glycyl-tRNA synthetase
GNAS GNAS complex locus
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIA4 glutamate receptor, ionotropic, AMPA 4
GTF2IRD1 GTF2I repeat domain containing 1
H3F3A H3 histone, family 3A
HMGN3 high mobility group nucleosomal binding domain 3
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IFT20 intraflagellar transport 20
IGHMBP2 immunoglobulin mu binding protein 2
IREB2 iron-responsive element binding protein 2
ITGB5 integrin, beta 5
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2
KCTD10 potassium channel tetramerization domain containing 10
KDM8 lysine (K)-specific demethylase 8
KIAA1549L KIAA1549-like
L1CAM L1 cell adhesion molecule
LARGE like-glycosyltransferase
LDLR low density lipoprotein receptor
LMNA lamin A/C
LPIN1 lipin 1
LTN1 listerin E3 ubiquitin protein ligase 1
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MBNL3 muscleblind-like splicing regulator 3
MCF2L MCF.2 cell line derived transforming sequence-like
MCU mitochondrial calcium uniporter
MECOM MDS1 and EVI1 complex locus
MECP2 methyl CpG binding protein 2
METTL24 methyltransferase like 24
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MIB2 mindbomb E3 ubiquitin protein ligase 2
MTA1 metastasis associated 1
MTM1 myotubularin 1
MUSK muscle, skeletal, receptor tyrosine kinase
MYBPC3 myosin binding protein C, cardiac
MYH1 myosin, heavy chain 1, skeletal muscle, adult
MYH4 myosin, heavy chain 4, skeletal muscle
MYO6 myosin VI
MYO7A myosin VIIA
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NKX1-1 NK1 homeobox 1
NMNAT1 nicotinamide nucleotide adenylyltransferase 1
NPC1 Niemann-Pick disease, type C1
NRCAM neuronal cell adhesion molecule
NRD1 nardilysin (N-arginine dibasic convertase)
NSUN2 NOP2/Sun RNA methyltransferase family, member 2
ORC4 origin recognition complex, subunit 4
PACS2 phosphofurin acidic cluster sorting protein 2
PARK7 parkinson protein 7
PITX3 paired-like homeodomain 3
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PMP22 peripheral myelin protein 22
POMK protein-O-mannose kinase
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PSEN1 presenilin 1
PSIP1 PC4 and SFRS1 interacting protein 1
PTCH1 patched 1
PTPRR protein tyrosine phosphatase, receptor type, R
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3
RHOBTB3 Rho-related BTB domain containing 3
RND3 Rho family GTPase 3
RNF7 ring finger protein 7
RORA RAR-related orphan receptor A
RPRD1B regulation of nuclear pre-mRNA domain containing 1B
RYR1 ryanodine receptor 1 (skeletal)
SCYL1 SCY1-like 1 (S. cerevisiae)
SEPP1 selenoprotein P, plasma, 1
SEPT8 septin 8
SHANK3 SH3 and multiple ankyrin repeat domains 3
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A38 solute carrier family 25, member 38
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC38A10 solute carrier family 38, member 10
SMN1 survival of motor neuron 1, telomeric
SMS spermine synthase
SRSF4 serine/arginine-rich splicing factor 4
STIM2 stromal interaction molecule 2
SURF1 surfeit 1
SYT7 synaptotagmin VII
SYTL1 synaptotagmin-like 1
TARDBP TAR DNA binding protein
TCTE1 t-complex-associated-testis-expressed 1
THRB thyroid hormone receptor, beta
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast)
TNC tenascin C
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TPCN2 two pore segment channel 2
TRDN triadin
TRIM32 tripartite motif containing 32
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TRPC3 transient receptor potential cation channel, subfamily C, member 3
UBE3B ubiquitin protein ligase E3B
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
USH1C Usher syndrome 1C (autosomal recessive, severe)
VCP valosin containing protein
VEGFA vascular endothelial growth factor A
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR37 WD repeat domain 37
XBP1 X-box binding protein 1
YIPF1 Yip1 domain family, member 1
ZMPSTE24 zinc metallopeptidase STE24
ZNF175 zinc finger protein 175