abnormal impulse conducting system conduction Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any functional anomaly in the impulse-conducting system composed of modified cardiac muscle and having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart (Mammalian Phenotype Ontology, MP_0003137)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003137
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75 gene mutations causing the abnormal impulse conducting system conduction phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
AKAP10 A kinase (PRKA) anchor protein 10
ANK2 ankyrin 2, neuronal
ASPH aspartate beta-hydroxylase
ATG5 autophagy related 5
BVES blood vessel epicardial substance
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CAMK2D calcium/calmodulin-dependent protein kinase II delta
COL1A1 collagen, type I, alpha 1
CXADR coxsackie virus and adenovirus receptor
DLL1 delta-like 1 (Drosophila)
DMD dystrophin
DMPK dystrophia myotonica-protein kinase
EGFR epidermal growth factor receptor
EMD emerin
EPHA3 EPH receptor A3
ESRRG estrogen-related receptor gamma
EYA3 EYA transcriptional coactivator and phosphatase 3
FOXP2 forkhead box P2
GAA glucosidase, alpha; acid
GJA1 gap junction protein, alpha 1, 43kDa
GJA5 gap junction protein, alpha 5, 40kDa
GJC1 gap junction protein, gamma 1, 45kDa
GJD3 gap junction protein, delta 3, 31.9kDa
GLA galactosidase, alpha
GNB5 guanine nucleotide binding protein (G protein), beta 5
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HOPX HOP homeobox
IDUA iduronidase, alpha-L-
IGHMBP2 immunoglobulin mu binding protein 2
IRX3 iroquois homeobox 3
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3
KCNIP2 Kv channel interacting protein 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KEL Kell blood group, metallo-endopeptidase
KL klotho
LMNA lamin A/C
LOC102723475 putative uncharacterized protein LOC388820
MIR208A microRNA 208a
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MYLK3 myosin light chain kinase 3
NHLH1 nescient helix loop helix 1
NKX2-5 NK2 homeobox 5
NUP155 nucleoporin 155kDa
PITX2 paired-like homeodomain 2
POPDC2 popeye domain containing 2
RGS6 regulator of G-protein signaling 6
RXRA retinoid X receptor, alpha
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN3B sodium channel, voltage gated, type III beta subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SMAD7 SMAD family member 7
SP4 Sp4 transcription factor
SYNE1 spectrin repeat containing, nuclear envelope 1
TBX3 T-box 3
TBX5 T-box 5
TH tyrosine hydroxylase
THRA thyroid hormone receptor, alpha
TNNT2 troponin T type 2 (cardiac)
VCL vinculin
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
XIRP1 xin actin binding repeat containing 1