abnormal intestinal goblet cell morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of a goblet cell that is part of the epithelium of intestinal villus (Mammalian Phenotype Ontology, MP_0003449)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003449
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45 gene mutations causing the abnormal intestinal goblet cell morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AGR2 anterior gradient 2
APC adenomatous polyposis coli
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLDN15 claudin 15
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYBA cytochrome b-245, alpha polypeptide
E2F4 E2F transcription factor 4, p107/p130-binding
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
FOXL1 forkhead box L1
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IL13 interleukin 13
IL17RE interleukin 17 receptor E
IL2 interleukin 2
IL25 interleukin 25
IL4 interleukin 4
IL5 interleukin 5
IL9 interleukin 9
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
KLF4 Kruppel-like factor 4 (gut)
LAMA5 laminin, alpha 5
LEP leptin
LTBP4 latent transforming growth factor beta binding protein 4
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MMP9 matrix metallopeptidase 9
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCF1 neutrophil cytosolic factor 1
NFIL3 nuclear factor, interleukin 3 regulated
PGLYRP1 peptidoglycan recognition protein 1
PGLYRP2 peptidoglycan recognition protein 2
PGLYRP3 peptidoglycan recognition protein 3
PGLYRP4 peptidoglycan recognition protein 4
SAV1 salvador family WW domain containing protein 1
SEC23B Sec23 homolog B (S. cerevisiae)
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPDEF SAM pointed domain containing ETS transcription factor
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
THRA thyroid hormone receptor, alpha
TLR4 toll-like receptor 4
YIPF6 Yip1 domain family, member 6