abnormal intraepithelial t cell morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of a T cell present in columnar epithelia such as in the gastrointestinal tract; intraepithelial T cells often have distinct developmental pathways and activation requirements (Mammalian Phenotype Ontology, MP_0008894)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008894
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Genes

22 gene mutations causing the abnormal intraepithelial t cell morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
B2M beta-2-microglobulin
CCL25 chemokine (C-C motif) ligand 25
CCR10 chemokine (C-C motif) receptor 10
CCR6 chemokine (C-C motif) receptor 6
CCR9 chemokine (C-C motif) receptor 9
CD247 CD247 molecule
CD8A CD8a molecule
CD8B CD8b molecule
FOXP3 forkhead box P3
IGHM immunoglobulin heavy constant mu
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL2 interleukin 2
IL2RG interleukin 2 receptor, gamma
LCK LCK proto-oncogene, Src family tyrosine kinase
PIGR polymeric immunoglobulin receptor
PTPRC protein tyrosine phosphatase, receptor type, C
RC3H1 ring finger and CCCH-type domains 1
RORC RAR-related orphan receptor C
TNF tumor necrosis factor
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