abnormal macrophage derived foam cell morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of a type of macrophage containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions (Mammalian Phenotype Ontology, MP_0008243)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008243
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7 gene mutations causing the abnormal macrophage derived foam cell morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADGRF5 adhesion G protein-coupled receptor F5
LDLR low density lipoprotein receptor
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
NPC1 Niemann-Pick disease, type C1
PLA2G15 phospholipase A2, group XV
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal