abnormal mast cell morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of a cell that is found in almost all tissues, containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation (Mammalian Phenotype Ontology, MP_0000359)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000359
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37 gene mutations causing the abnormal mast cell morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AGR2 anterior gradient 2
C3 complement component 3
CCR1 chemokine (C-C motif) receptor 1
CD44 CD44 molecule (Indian blood group)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CPA3 carboxypeptidase A3 (mast cell)
DSG3 desmoglein 3
FBN1 fibrillin 1
GAB2 GRB2-associated binding protein 2
HDC histidine decarboxylase
IL3 interleukin 3
IL5 interleukin 5
IL9 interleukin 9
ITGB7 integrin, beta 7
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
LYN LYN proto-oncogene, Src family tyrosine kinase
LYST lysosomal trafficking regulator
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MITF microphthalmia-associated transcription factor
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
PLA2G3 phospholipase A2, group III
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PTGDR prostaglandin D2 receptor (DP)
PTGDS prostaglandin D2 synthase 21kDa (brain)
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
SELE selectin E
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SHARPIN SHANK-associated RH domain interactor
SPRED1 sprouty-related, EVH1 domain containing 1
SRGN serglycin
STAT5A signal transducer and activator of transcription 5A
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
T T, brachyury homolog (mouse)
TPSAB1 tryptase alpha/beta 1
WAS Wiskott-Aldrich syndrome