abnormal memory b cell differentiation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description atypical production of or inability to produce distinctly differentiated long-lived B cells that are readily activated upon reencounter of an antigenic determinant; memory B cells differentiate from antigen-activated B cells which have been selected for expression of higher affinity immunoglobulin (Mammalian Phenotype Ontology, MP_0008095)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008095
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3 gene mutations causing the abnormal memory b cell differentiation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CR2 complement component (3d/Epstein Barr virus) receptor 2
FCAMR Fc receptor, IgA, IgM, high affinity
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)