abnormal mesenteric lymph node morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the lymph nodes located in the mesentery, of which there are 3 classes: ileocolic, juxtaintestinal mesenteric, and central superior group (Mammalian Phenotype Ontology, MP_0005232)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005232
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38 gene mutations causing the abnormal mesenteric lymph node morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ANGPTL4 angiopoietin-like 4
BIRC3 baculoviral IAP repeat containing 3
CCL25 chemokine (C-C motif) ligand 25
CCR9 chemokine (C-C motif) receptor 9
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
F2R coagulation factor II (thrombin) receptor
FOXP3 forkhead box P3
IFNG interferon, gamma
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10RB interleukin 10 receptor, beta
IL2 interleukin 2
IL25 interleukin 25
IL2RG interleukin 2 receptor, gamma
IL7 interleukin 7
JAK3 Janus kinase 3
LIPA lipase A, lysosomal acid, cholesterol esterase
LTA lymphotoxin alpha
LTB lymphotoxin beta (TNF superfamily, member 3)
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MAP3K14 mitogen-activated protein kinase kinase kinase 14
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NKX2-3 NK2 homeobox 3
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RUNX3 runt-related transcription factor 3
S1PR3 sphingosine-1-phosphate receptor 3
SHARPIN SHANK-associated RH domain interactor
SMAD3 SMAD family member 3
SPHK1 sphingosine kinase 1
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TOX thymocyte selection-associated high mobility group box
TXNIP thioredoxin interacting protein