abnormal midbrain-hindbrain boundary development Gene Set

Dataset	MPO Gene-Phenotype Associations
Category	disease or phenotype associations
Type	phenotype
Description	anomaly in the formation of the midbrain-hindbrain domain, comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages; an organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate (Mammalian Phenotype Ontology, MP_0004096)
External Link	http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004096
Similar Terms
Downloads & Tools

Genes

9 gene mutations causing the abnormal midbrain-hindbrain boundary development phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol	Name
GBX2	gastrulation brain homeobox 2
HESX1	HESX homeobox 1
HIRA	histone cell cycle regulator
HSD17B7	hydroxysteroid (17-beta) dehydrogenase 7
LMX1B	LIM homeobox transcription factor 1, beta
MID1	midline 1
OTX2	orthodenticle homeobox 2
SSBP3	single stranded DNA binding protein 3
WNT1	wingless-type MMTV integration site family, member 1