abnormal midbrain-hindbrain boundary development Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the formation of the midbrain-hindbrain domain, comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages; an organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate (Mammalian Phenotype Ontology, MP_0004096)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004096
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9 gene mutations causing the abnormal midbrain-hindbrain boundary development phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
GBX2 gastrulation brain homeobox 2
HESX1 HESX homeobox 1
HIRA histone cell cycle regulator
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
LMX1B LIM homeobox transcription factor 1, beta
MID1 midline 1
OTX2 orthodenticle homeobox 2
SSBP3 single stranded DNA binding protein 3
WNT1 wingless-type MMTV integration site family, member 1