abnormal neutrophil differentiation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description atypical production of or inability to produce the granular leukocytes that have a three- to five-lobed nucleus and a cytoplasm that contains inconspicuous granules stainable by neutral dyes (Mammalian Phenotype Ontology, MP_0002415)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002415
Similar Terms
Downloads & Tools


9 gene mutations causing the abnormal neutrophil differentiation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CSF3R colony stimulating factor 3 receptor (granulocyte)
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
KMT2E lysine (K)-specific methyltransferase 2E
LBR lamin B receptor
MECOM MDS1 and EVI1 complex locus
MIR223 microRNA 223
PLSCR1 phospholipid scramblase 1
SPI1 Spi-1 proto-oncogene