abnormal nk t cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description deviation from the normal number of the distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repertoire of variable region gene segments (Mammalian Phenotype Ontology, MP_0008038)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008038
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51 gene mutations causing the abnormal nk t cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AIRE autoimmune regulator
ARID4A AT rich interactive domain 4A (RBP1-like)
ATF2 activating transcription factor 2
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
C10ORF11 chromosome 10 open reading frame 11
CARD11 caspase recruitment domain family, member 11
CCR4 chemokine (C-C motif) receptor 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD1D CD1d molecule
CD247 CD247 molecule
CXCL16 chemokine (C-X-C motif) ligand 16
ELF4 E74-like factor 4 (ets domain transcription factor)
FARSA phenylalanyl-tRNA synthetase, alpha subunit
GIMAP6 GTPase, IMAP family member 6
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFNG interferon, gamma
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL17RB interleukin 17 receptor B
IRF1 interferon regulatory factor 1
ITK IL2-inducible T-cell kinase
KMT2E lysine (K)-specific methyltransferase 2E
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LYST lysosomal trafficking regulator
MAP3K14 mitogen-activated protein kinase kinase kinase 14
NFIL3 nuclear factor, interleukin 3 regulated
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NHEJ1 nonhomologous end-joining factor 1
PCSK1 proprotein convertase subtilisin/kexin type 1
PRDX1 peroxiredoxin 1
PRKCQ protein kinase C, theta
RAG2 recombination activating gene 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHOH ras homolog family member H
SAP130 Sin3A-associated protein, 130kDa
SH2D1A SH2 domain containing 1A
SMS spermine synthase
SOCS1 suppressor of cytokine signaling 1
SPNS2 spinster homolog 2 (Drosophila)
STAT1 signal transducer and activator of transcription 1, 91kDa
TBK1 TANK-binding kinase 1
TBX21 T-box 21
TMEM127 transmembrane protein 127
TMEM98 transmembrane protein 98
TOX thymocyte selection-associated high mobility group box
TXNIP thioredoxin interacting protein
VAV1 vav 1 guanine nucleotide exchange factor
ZBTB16 zinc finger and BTB domain containing 16
ZNF335 zinc finger protein 335
ZP1 zona pellucida glycoprotein 1 (sperm receptor)