abnormal object recognition memory Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the ability to recognize objects that the animal has previously encountered; recognition is measured by relative amount of time exploring objects, which should decrease upon subsequent or multiple presentations of the same object when presented with novel objects at the same time (Mammalian Phenotype Ontology, MP_0001458)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001458
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Genes

48 gene mutations causing the abnormal object recognition memory phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
APP amyloid beta (A4) precursor protein
ARC activity-regulated cytoskeleton-associated protein
BAIAP2 BAI1-associated protein 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CARF calcium responsive transcription factor
CREBBP CREB binding protein
CSK c-src tyrosine kinase
DCDC2 doublecortin domain containing 2
EGR1 early growth response 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
FMR1 fragile X mental retardation 1
FOXO6 forkhead box O6
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GAL galanin/GMAP prepropeptide
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GRIA4 glutamate receptor, ionotropic, AMPA 4
HDAC3 histone deacetylase 3
IL6 interleukin 6
ITM2B integral membrane protein 2B
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KIF17 kinesin family member 17
KL klotho
MAPT microtubule-associated protein tau
MECP2 methyl CpG binding protein 2
NCOR1 nuclear receptor corepressor 1
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1
NOS3 nitric oxide synthase 3 (endothelial cell)
NPC1 Niemann-Pick disease, type C1
NPY2R neuropeptide Y receptor Y2
NQO2 NAD(P)H dehydrogenase, quinone 2
RGS14 regulator of G-protein signaling 14
SHANK3 SH3 and multiple ankyrin repeat domains 3
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SYN2 synapsin II
THRA thyroid hormone receptor, alpha
TNIK TRAF2 and NCK interacting kinase
WASF1 WAS protein family, member 1
Funding