abnormal optic vesicle formation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomalous formation of the hollow outgrowth from the lateral aspects of the embryonic forebrain from which the retina and optic nerve develop (Mammalian Phenotype Ontology, MP_0003425)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003425
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26 gene mutations causing the abnormal optic vesicle formation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ATOH7 atonal homolog 7 (Drosophila)
COL2A1 collagen, type II, alpha 1
CSNK2A1 casein kinase 2, alpha 1 polypeptide
DISP1 dispatched homolog 1 (Drosophila)
DKK1 dickkopf WNT signaling pathway inhibitor 1
FOLR1 folate receptor 1 (adult)
GLI3 GLI family zinc finger 3
HESX1 HESX homeobox 1
HHAT hedgehog acyltransferase
HHEX hematopoietically expressed homeobox
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
LHX2 LIM homeobox 2
MAB21L2 mab-21-like 2 (C. elegans)
MSX2 msh homeobox 2
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NCSTN nicastrin
OTX2 orthodenticle homeobox 2
PAX6 paired box 6
RAX retina and anterior neural fold homeobox
RDH10 retinol dehydrogenase 10 (all-trans)
RERE arginine-glutamic acid dipeptide (RE) repeats
SHH sonic hedgehog
SIX3 SIX homeobox 3
SMO smoothened, frizzled class receptor
TCOF1 Treacher Collins-Franceschetti syndrome 1
ZIC5 Zic family member 5