abnormal pancreatic islet size Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the size of the clusters of hormone-producing cells that are scattered throughout the pancreas (Mammalian Phenotype Ontology, MP_0009170)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009170
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76 gene mutations causing the abnormal pancreatic islet size phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALMS1 Alstrom syndrome protein 1
ALX3 ALX homeobox 3
ANXA7 annexin A7
AQP7 aquaporin 7
ATXN2 ataxin 2
BAD BCL2-associated agonist of cell death
BGLAP bone gamma-carboxyglutamate (gla) protein
BRD2 bromodomain containing 2
CCDC80 coiled-coil domain containing 80
CDK4 cyclin-dependent kinase 4
CES1 carboxylesterase 1
CLOCK clock circadian regulator
COL1A1 collagen, type I, alpha 1
CPE carboxypeptidase E
CTF1 cardiotrophin 1
DACH1 dachshund family transcription factor 1
E2F1 E2F transcription factor 1
EHD4 EH-domain containing 4
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ESR2 estrogen receptor 2 (ER beta)
FFAR4 free fatty acid receptor 4
FSTL3 follistatin-like 3 (secreted glycoprotein)
GCGR glucagon receptor
GCK glucokinase (hexokinase 4)
GDF11 growth differentiation factor 11
GHR growth hormone receptor
GLIS3 GLIS family zinc finger 3
HHIP hedgehog interacting protein
HIPK3 homeodomain interacting protein kinase 3
HMGA1 high mobility group AT-hook 1
INS insulin
INSL5 insulin-like 5
INSM1 insulinoma-associated 1
INVS inversin
IRS2 insulin receptor substrate 2
KL klotho
KMT2B lysine (K)-specific methyltransferase 2B
LEP leptin
LEPR leptin receptor
LIPE lipase, hormone-sensitive
MEN1 multiple endocrine neoplasia I
MGMT O-6-methylguanine-DNA methyltransferase
MNX1 motor neuron and pancreas homeobox 1
MPG N-methylpurine-DNA glycosylase
MYD88 myeloid differentiation primary response 88
NCOA5 nuclear receptor coactivator 5
NKX2-2 NK2 homeobox 2
NKX6-1 NK6 homeobox 1
OPRM1 opioid receptor, mu 1
PAX2 paired box 2
PDPK1 3-phosphoinositide dependent protein kinase 1
PDX1 pancreatic and duodenal homeobox 1
PGR progesterone receptor
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PPARG peroxisome proliferator-activated receptor gamma
PRKCI protein kinase C, iota
PRLR prolactin receptor
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RBM4 RNA binding motif protein 4
RBM4B RNA binding motif protein 4B
RIMS2 regulating synaptic membrane exocytosis 2
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SCG5 secretogranin V
SH2B1 SH2B adaptor protein 1
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SOCS7 suppressor of cytokine signaling 7
SOX9 SRY (sex determining region Y)-box 9
THBS1 thrombospondin 1
THRA thyroid hormone receptor, alpha
TLR2 toll-like receptor 2
TNK1 tyrosine kinase, non-receptor, 1
TOP3B topoisomerase (DNA) III beta
TUB tubby bipartite transcription factor