abnormal perineural vascular plexus morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the capillary bed that initially surrounds the relative avascular brain and spinal cord; the perineural vascular plexus (PNVP) is the precursor to the blood brain barrier formed by angioblasts which migrate away from somites and is recruited to surround the neural tube in response to VEGF; vascularization of the brain and spinal cord occurs via angiogenesis as sprouting vessels from the PNVP invade the neuroepithelium and grow inward toward the ventricular lumen (Mammalian Phenotype Ontology, MP_0012732)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0012732
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5 gene mutations causing the abnormal perineural vascular plexus morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADGRA2 adhesion G protein-coupled receptor A2
ENG endoglin
FLT4 fms-related tyrosine kinase 4
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
ZMIZ1 zinc finger, MIZ-type containing 1