abnormal pituitary gland size Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the average size of the compound gland suspended from the base of the hypothalamus (Mammalian Phenotype Ontology, MP_0008936)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008936
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33 gene mutations causing the abnormal pituitary gland size phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AES amino-terminal enhancer of split
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CSHL1 chorionic somatomammotropin hormone-like 1
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
DDR2 discoidin domain receptor tyrosine kinase 2
DISP1 dispatched homolog 1 (Drosophila)
DRD2 dopamine receptor D2
GHR growth hormone receptor
GHRH growth hormone releasing hormone
GHRHR growth hormone releasing hormone receptor
GSX1 GS homeobox 1
HES1 hes family bHLH transcription factor 1
HMX2 H6 family homeobox 2
HMX3 H6 family homeobox 3
INSM1 insulinoma-associated 1
IRS2 insulin receptor substrate 2
MARK2 MAP/microtubule affinity-regulating kinase 2
MBD5 methyl-CpG binding domain protein 5
MEN1 multiple endocrine neoplasia I
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
PITX2 paired-like homeodomain 2
PRL prolactin
PROP1 PROP paired-like homeobox 1
PTPRS protein tyrosine phosphatase, receptor type, S
SERP1 stress-associated endoplasmic reticulum protein 1
SIM1 single-minded family bHLH transcription factor 1
SIX6 SIX homeobox 6
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
THRB thyroid hormone receptor, beta
WWOX WW domain containing oxidoreductase