abnormal prostaglandin level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the amount in the body of any of a class of mediators with effects of vasodilation, vasoconstriction, and smooth muscle stimulation (Mammalian Phenotype Ontology, MP_0009811)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009811
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Genes

26 gene mutations causing the abnormal prostaglandin level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACSL4 acyl-CoA synthetase long-chain family member 4
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
APC adenomatous polyposis coli
APOE apolipoprotein E
CYSLTR2 cysteinyl leukotriene receptor 2
DUSP1 dual specificity phosphatase 1
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
LEPR leptin receptor
LPAR3 lysophosphatidic acid receptor 3
MMP9 matrix metallopeptidase 9
NOS3 nitric oxide synthase 3 (endothelial cell)
PLA2G10 phospholipase A2, group X
PTGDR2 prostaglandin D2 receptor 2
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGES prostaglandin E synthase
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SLCO2A1 solute carrier organic anion transporter family, member 2A1
XPA xeroderma pigmentosum, complementation group A
Funding