abnormal pulmonary artery morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the artery that arises from the right ventricle and conveys unaerated blood to the lungs (Mammalian Phenotype Ontology, MP_0000484)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000484
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42 gene mutations causing the abnormal pulmonary artery morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADAM19 ADAM metallopeptidase domain 19
ADORA2A adenosine A2a receptor
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
C5ORF42 chromosome 5 open reading frame 42
CAV1 caveolin 1, caveolae protein, 22kDa
CDO1 cysteine dioxygenase type 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
DDAH1 dimethylarginine dimethylaminohydrolase 1
DNAH5 dynein, axonemal, heavy chain 5
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ELN elastin
EPAS1 endothelial PAS domain protein 1
FGF10 fibroblast growth factor 10
FGFR2 fibroblast growth factor receptor 2
FOXM1 forkhead box M1
FUZ fuzzy planar cell polarity protein
GJA5 gap junction protein, alpha 5, 40kDa
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIF3A hypoxia inducible factor 3, alpha subunit
IFT88 intraflagellar transport 88
JMJD6 jumonji domain containing 6
KIF7 kinesin family member 7
LOX lysyl oxidase
MGP matrix Gla protein
NOS3 nitric oxide synthase 3 (endothelial cell)
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NRP1 neuropilin 1
NTF3 neurotrophin 3
PLVAP plasmalemma vesicle associated protein
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTK7 protein tyrosine kinase 7 (inactive)
RARB retinoic acid receptor, beta
RERE arginine-glutamic acid dipeptide (RE) repeats
RXRA retinoid X receptor, alpha
SDPR serum deprivation response
SHH sonic hedgehog
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
TBC1D32 TBC1 domain family, member 32
TGFB2 transforming growth factor, beta 2
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
VIP vasoactive intestinal peptide