| Dataset | MGI Mouse Phenotype Associations 2023 |
| Category | disease or phenotype associations |
| Type | phenotype |
| Description | any structural anomaly of the specialized subpopulation of T cells that act to suppress activation of the immune system and thus maintain immune system homeostasis and prevent pathological self-reactivity; these may include T cells that express the CD8 transmembrane glycoprotein (CD8-positive T cells), those that express CD4 and CD25 (CD4-positive, CD25-positive regulatory T cells or Tregs) and other T cell types that have suppressor function (Mammalian Phenotype Ontology, MP_0004941) |
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4 gene mutations causing the abnormal regulatory T cell morphology phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.
