abnormal renal glomerulus basement membrane thickness Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increased or decreased width of the layer of extracellular matrix that lies between the endothelium of the glomerular capillaries and the podocytes of the inner or visceral layer of the Bowman capsule (Mammalian Phenotype Ontology, MP_0011349)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011349
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22 gene mutations causing the abnormal renal glomerulus basement membrane thickness phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AGER advanced glycosylation end product-specific receptor
ASIP agouti signaling protein
CD151 CD151 molecule (Raph blood group)
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
DDR1 discoidin domain receptor tyrosine kinase 1
E2F2 E2F transcription factor 2
FAS Fas cell surface death receptor
GDNF glial cell derived neurotrophic factor
GRM1 glutamate receptor, metabotropic 1
INS insulin
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
LAMB2 laminin, beta 2 (laminin S)
LEP leptin
LMX1B LIM homeobox transcription factor 1, beta
MTSS1 metastasis suppressor 1
MYO1E myosin IE
PKN1 protein kinase N1
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
SMAD3 SMAD family member 3
VEGFA vascular endothelial growth factor A
WT1 Wilms tumor 1