abnormal response/metabolism to endogenous compounds Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description altered ability or inability to metabolize or respond to substances normally present in the body (Mammalian Phenotype Ontology, MP_0003638)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003638
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91 gene mutations causing the abnormal response/metabolism to endogenous compounds phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ADAM8 ADAM metallopeptidase domain 8
ADORA1 adenosine A1 receptor
ADORA3 adenosine A3 receptor
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHM choroideremia (Rab escort protein 1)
CLEC4M C-type lectin domain family 4, member M
COL3A1 collagen, type III, alpha 1
CPA3 carboxypeptidase A3 (mast cell)
CTSA cathepsin A
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
DIO1 deiodinase, iodothyronine, type I
DRD1 dopamine receptor D1
EPHA1 EPH receptor A1
ERN1 endoplasmic reticulum to nucleus signaling 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FABP7 fatty acid binding protein 7, brain
FOXQ1 forkhead box Q1
GHSR growth hormone secretagogue receptor
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAS GNAS complex locus
GPER1 G protein-coupled estrogen receptor 1
GRPR gastrin-releasing peptide receptor
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HDAC2 histone deacetylase 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-E major histocompatibility complex, class I, E
HRH1 histamine receptor H1
HSPA1B heat shock 70kDa protein 1B
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IGF1 insulin-like growth factor 1 (somatomedin C)
IL1R1 interleukin 1 receptor, type I
IL20RB interleukin 20 receptor beta
IL23R interleukin 23 receptor
ITGB6 integrin, beta 6
KAT6A K(lysine) acetyltransferase 6A
KCP kielin/chordin-like protein
KISS1R KISS1 receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LASP1 LIM and SH3 protein 1
LEPR leptin receptor
LRP2 low density lipoprotein receptor-related protein 2
LRRK2 leucine-rich repeat kinase 2
MMP9 matrix metallopeptidase 9
NCOA1 nuclear receptor coactivator 1
NCOR1 nuclear receptor corepressor 1
NMUR1 neuromedin U receptor 1
NMUR2 neuromedin U receptor 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NR1I3 nuclear receptor subfamily 1, group I, member 3
NT5E 5'-nucleotidase, ecto (CD73)
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PACS2 phosphofurin acidic cluster sorting protein 2
PAH phenylalanine hydroxylase
PARP1 poly (ADP-ribose) polymerase 1
PBX1 pre-B-cell leukemia homeobox 1
PDC phosducin
PDYN prodynorphin
PGR progesterone receptor
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLD2 phospholipase D2
POMC proopiomelanocortin
PRCP prolylcarboxypeptidase (angiotensinase C)
PROS1 protein S (alpha)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PYY peptide YY
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RARG retinoic acid receptor, gamma
RB1 retinoblastoma 1
REG1B regenerating islet-derived 1 beta
RNLS renalase, FAD-dependent amine oxidase
S100A10 S100 calcium binding protein A10
SCT secretin
SCTR secretin receptor
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TGIF1 TGFB-induced factor homeobox 1
THRA thyroid hormone receptor, alpha
THRB thyroid hormone receptor, beta
TNFRSF19 tumor necrosis factor receptor superfamily, member 19
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TTN titin
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
XIRP2 xin actin binding repeat containing 2