abnormal response to radiation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any anomaly in the physiological changes induced by ionizing radiation such as UV light, X-rays, or gamma rays (Mammalian Phenotype Ontology, MP_0012734)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0012734
Similar Terms
Downloads & Tools


43 gene mutations causing the abnormal response to radiation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ATM ATM serine/threonine kinase
BID BH3 interacting domain death agonist
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CCNG1 cyclin G1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHEK2 checkpoint kinase 2
COPS6 COP9 signalosome subunit 6
ERC1 ELKS/RAB6-interacting/CAST family member 1
EWSR1 EWS RNA-binding protein 1
FUS FUS RNA binding protein
GPX4 glutathione peroxidase 4
H2AFX H2A histone family, member X
HMGN1 high mobility group nucleosome binding domain 1
ING1 inhibitor of growth family, member 1
IP6K2 inositol hexakisphosphate kinase 2
JAM2 junctional adhesion molecule 2
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KITLG KIT ligand
KMT2E lysine (K)-specific methyltransferase 2E
MCPH1 microcephalin 1
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MUS81 MUS81 structure-specific endonuclease subunit
NBN nibrin
NOS2 nitric oxide synthase 2, inducible
PARG poly (ADP-ribose) glycohydrolase
PARP1 poly (ADP-ribose) polymerase 1
PARP2 poly (ADP-ribose) polymerase 2
PER2 period circadian clock 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTCH1 patched 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RPL27A ribosomal protein L27a
SNAI2 snail family zinc finger 2
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
UIMC1 ubiquitin interaction motif containing 1
USP1 ubiquitin specific peptidase 1