|Dataset||MPO Gene-Phenotype Associations|
|Category||disease or phenotype associations|
|Description||altered ability of the Sertoli cells to endocytose and degrade the apoptotic spermatogenic cells and residual bodies (shed cytoplasts) during the maturation phase of spermiogenesis; normally, greater than 50 per cent of differentiating spermatogenic cells undergo apoptosis before maturing into spermatozoa, and these cells are selectively and rapidly eliminated through phagocytosis by Sertoli cells (Mammalian Phenotype Ontology, MP_0009851)|
|Downloads & Tools|
4 gene mutations causing the abnormal sertoli cell phagocytosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.