An anomaly in the communication from a neuron to a target across a synapse. This is a four step process, comprising (i) synthesis and storage of neurotransmitters; (ii) neurotransmitter release; (iii) activation of postsynaptic receptors by the neurotransmitter; and (iv) inactivation of the neurotransmitter. Thus, this term is defined as an anomaly of neurotransmitter metabolic process. (Human Phenotype Ontology, HP_0012535)
14 genes associated with the abnormal synaptic transmission phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.