abnormal testis cord formation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly in the formation of the attachments derived from the primordial seminiferous cords that differentiate into seminiferous tubules in adolescence; defective testis cord formation is most likely to reflect abnormal function of either Sertoli cells or peritubular myoid (PTM) cells which normally cooperate to deposit a layer of basal lamina that defines the edges of individual testis cords (Mammalian Phenotype Ontology, MP_0006418)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0006418
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9 gene mutations causing the abnormal testis cord formation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
DHH desert hedgehog
FGF9 fibroblast growth factor 9
GADD45G growth arrest and DNA-damage-inducible, gamma
MAP3K4 mitogen-activated protein kinase kinase kinase 4
NR0B1 nuclear receptor subfamily 0, group B, member 1
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
SGPL1 sphingosine-1-phosphate lyase 1
SMAD1 SMAD family member 1
TCF21 transcription factor 21