abnormal thymocyte apoptosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description change in the timing or the number of immature T cells located in the thymus that are undergoing programmed cell death (Mammalian Phenotype Ontology, MP_0009258)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009258
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37 gene mutations causing the abnormal thymocyte apoptosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BIRC6 baculoviral IAP repeat containing 6
BRAF B-Raf proto-oncogene, serine/threonine kinase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CD247 CD247 molecule
CDK6 cyclin-dependent kinase 6
COPS6 COP9 signalosome subunit 6
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DTX1 deltex 1, E3 ubiquitin ligase
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAIM Fas apoptotic inhibitory molecule
IL15RA interleukin 15 receptor, alpha
ING1 inhibitor of growth family, member 1
KIFAP3 kinesin-associated protein 3
KLF13 Kruppel-like factor 13
LCN2 lipocalin 2
MAP2K6 mitogen-activated protein kinase kinase 6
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
NDRG1 N-myc downstream regulated 1
NHEJ1 nonhomologous end-joining factor 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PERP PERP, TP53 apoptosis effector
PNP purine nucleoside phosphorylase
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RORC RAR-related orphan receptor C
RUNX1 runt-related transcription factor 1
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TMEM109 transmembrane protein 109
TP53 tumor protein p53
TP73 tumor protein p73
TRAF2 TNF receptor-associated factor 2
TWSG1 twisted gastrulation BMP signaling modulator 1
USP4 ubiquitin specific peptidase 4 (proto-oncogene)