abnormal vascular branching morphogenesis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase, decrease or anomaly in the process by which new vessels sprout off pre-existing vessels (Mammalian Phenotype Ontology, MP_0003227)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003227
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27 gene mutations causing the abnormal vascular branching morphogenesis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADAM10 ADAM metallopeptidase domain 10
ADGRA2 adhesion G protein-coupled receptor A2
ANGPT1 angiopoietin 1
APH1A APH1A gamma secretase subunit
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
CCM2 cerebral cavernous malformation 2
CREBBP CREB binding protein
DLL4 delta-like 4 (Drosophila)
EPHB4 EPH receptor B4
GIPC1 GIPC PDZ domain containing family, member 1
ITGB8 integrin, beta 8
MAPK7 mitogen-activated protein kinase 7
MEIS1 Meis homeobox 1
MYH9 myosin, heavy chain 9, non-muscle
NOS3 nitric oxide synthase 3 (endothelial cell)
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPRJ protein tyrosine phosphatase, receptor type, J
RUNX1 runt-related transcription factor 1
S1PR1 sphingosine-1-phosphate receptor 1
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
TEK TEK tyrosine kinase, endothelial
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TIMP3 TIMP metallopeptidase inhibitor 3
VEGFA vascular endothelial growth factor A
WNK1 WNK lysine deficient protein kinase 1
ZMIZ1 zinc finger, MIZ-type containing 1