abnormal vitelline vascular remodeling Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the conversion of the primary (honeycomb-like) vascular plexus of the yolk sac into a mature vascular network (Mammalian Phenotype Ontology, MP_0004076)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004076
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56 gene mutations causing the abnormal vitelline vascular remodeling phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACVRL1 activin A receptor type II-like 1
APH1A APH1A gamma secretase subunit
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ATP7A ATPase, Cu++ transporting, alpha polypeptide
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCM2 cerebral cavernous malformation 2
CCNF cyclin F
CHM choroideremia (Rab escort protein 1)
CUBN cubilin (intrinsic factor-cobalamin receptor)
DICER1 dicer 1, ribonuclease type III
DLL4 delta-like 4 (Drosophila)
EFNB2 ephrin-B2
EPHB4 EPH receptor B4
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FLT4 fms-related tyrosine kinase 4
FN1 fibronectin 1
FOXO1 forkhead box O1
FZD5 frizzled class receptor 5
HAND1 heart and neural crest derivatives expressed 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
JAG1 jagged 1
KAT7 K(lysine) acetyltransferase 7
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK14 mitogen-activated protein kinase 14
MAPK7 mitogen-activated protein kinase 7
MIB1 mindbomb E3 ubiquitin protein ligase 1
MYL7 myosin, light chain 7, regulatory
NSDHL NAD(P) dependent steroid dehydrogenase-like
OVOL2 ovo-like zinc finger 2
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
POGLUT1 protein O-glucosyltransferase 1
PPAP2B phosphatidic acid phosphatase type 2B
PTK2 protein tyrosine kinase 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRB protein tyrosine phosphatase, receptor type, B
PTPRJ protein tyrosine phosphatase, receptor type, J
RASIP1 Ras interacting protein 1
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RUNX1 runt-related transcription factor 1
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SMAD5 SMAD family member 5
SOX7 SRY (sex determining region Y)-box 7
TBX20 T-box 20
TEK TEK tyrosine kinase, endothelial
TGFBR1 transforming growth factor, beta receptor 1
TMEM100 transmembrane protein 100
TTN titin
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UBR5 ubiquitin protein ligase E3 component n-recognin 5
WASF2 WAS protein family, member 2
WNK1 WNK lysine deficient protein kinase 1
ZMIZ1 zinc finger, MIZ-type containing 1