abnormality of pain sensation Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description Pain is an unpleasant sensation that can range from mild, localized discomfort to agony, whereby the physical part of pain results from nerve stimulation and is often accompanied by an emotional component. This term groups abnormalities in pain sensation presumed to result from abnormalities related to the specific nerve fibers that carry the pain impulses to the brain. (Human Phenotype Ontology, HP_0010832)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0010832
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25 genes associated with the abnormality of pain sensation phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
FBN1 fibrillin 1
FLII flightless I homolog (Drosophila)
GJB1 gap junction protein, beta 1, 32kDa
H19 H19, imprinted maternally expressed transcript (non-protein coding)
HDAC4 histone deacetylase 4
IGF2 insulin-like growth factor 2
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
KCNQ1OT1 KCNQ1 opposite strand/antisense transcript 1 (non-protein coding)
LIFR leukemia inhibitory factor receptor alpha
MFN2 mitofusin 2
MPV17 MpV17 mitochondrial inner membrane protein
NDN necdin, melanoma antigen (MAGE) family member
NGF nerve growth factor (beta polypeptide)
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OPA1 optic atrophy 1 (autosomal dominant)
PRPS1 phosphoribosyl pyrophosphate synthetase 1
RAI1 retinoic acid induced 1
SCN11A sodium channel, voltage gated, type XI alpha subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SHANK3 SH3 and multiple ankyrin repeat domains 3
SNRPN small nuclear ribonucleoprotein polypeptide N
WFS1 Wolfram syndrome 1 (wolframin)